C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CDC42 binding protein kinase alpha (DMPK-like)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143776 CDC42BPA 9606 - 1:226989865-227318474 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000334218 CDC42BPA-003 226989865-227317714 protein_coding
  ENST00000366764 CDC42BPA-201 226989866-227318125 protein_coding
  ENST00000366766 CDC42BPA-202 226989866-227318125 protein_coding
  ENST00000366767 CDC42BPA-002 226989865-227317182 protein_coding
  ENST00000366769 CDC42BPA-001 226989865-227318474 protein_coding
  ENST00000429440 CDC42BPA-007 227004055-227034717 protein_coding
  ENST00000441725 CDC42BPA-005 227023263-227074364 protein_coding
  ENST00000442054 CDC42BPA-004 226993627-227101120 protein_coding
  ENST00000448940 CDC42BPA-006 226989866-227080979 protein_coding
  ENST00000462553 CDC42BPA-009 227199557-227254155 processed_transcript
  ENST00000466538 CDC42BPA-011 227111984-227112799 processed_transcript
  ENST00000478573 CDC42BPA-010 227193651-227317047 retained_intron
  ENST00000488131 CDC42BPA-008 227068467-227081017 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000334218ENST00000366764ENST00000366766ENST00000366767ENST00000366769ENST00000442054ENST00000448940ENST00000466538
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000334218 N/A N/A N/A 3.256±0.00 N/A N/A 0.807±0.20 N/A N/A N/A 0.169±0.00 N/A N/A N/A
ENST00000366764 N/A N/A N/A 2.968±0.20 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.653±0.00
ENST00000366766 3.071±0.00 1.236±0.00 N/A N/A N/A 2.502±0.00 N/A 1.758±0.00 N/A 0.801±0.00 0.472±0.00 1.033±0.00 0.787±0.42 5.341±0.00
ENST00000366767 4.049±0.00 1.362±0.00 N/A 3.932±0.00 1.689±0.38 3.480±0.00 1.181±0.00 1.564±0.02 1.718±1.33 2.275±1.00 N/A 1.896±1.15 1.229±0.60 3.052±0.51
ENST00000366769 2.054±0.00 N/A 3.374±0.00 N/A 1.823±0.00 3.041±0.35 0.756±0.00 0.754±0.28 2.864±2.28 1.050±0.00 0.400±0.00 1.624±0.56 0.649±0.00 2.002±0.00
ENST00000442054 N/A N/A N/A N/A N/A N/A N/A 2.473±0.00 N/A N/A N/A N/A N/A 4.524±0.00
ENST00000448940 N/A 1.854±0.00 N/A 3.612±0.00 2.875±0.00 3.915±0.00 1.416±0.00 4.709±0.00 1.436±0.00 0.900±0.00 0.893±0.45 4.192±2.48 1.848±0.03 6.751±0.00
ENST00000466538 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.332±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008CY CIL_0008CY_0001 VISTA 1:226526998-227129223
CIL_000985 CIL_000985_0001 VISTA 1:226618699-227222072

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000226 IEA microtubule cytoskeleton organization
GO:0000287 IDA magnesium ion binding
GO:0004672 IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005911 ISS cell-cell junction
GO:0006468 IDA:IEA protein phosphorylation
GO:0007097 IEA nuclear migration
GO:0016477 IMP cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031032 IMP actomyosin structure organization
GO:0031252 ISS cell leading edge
GO:0031532 IDA actin cytoskeleton reorganization
GO:0035556 IEA intracellular signal transduction
GO:0042641 IDA actomyosin
GO:0042802 IPI identical protein binding
GO:0050790 IEA regulation of catalytic activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016464 CDC42BPA (1 of 2) CDC42 binding protein kinase alpha (DMPK-like) protein_coding Danio_rerio
ENSDARG00000058760 CDC42BPA (2 of 2) CDC42 binding protein kinase alpha (DMPK-like) protein_coding Danio_rerio
ENSMUSG00000026490 Cdc42bpa CDC42 binding protein kinase alpha protein_coding Mus_musculus

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