C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 2A, 65kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000144895 EIF2A 9606 + 3:150546678-150584242 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000273435 EIF2A-004 150546794-150584242 protein_coding
  ENST00000406576 EIF2A-003 150546787-150584115 protein_coding
  ENST00000460851 EIF2A-001 150546694-150584242 protein_coding
  ENST00000462221 EIF2A-013 150546814-150572061 nonsense_mediated_decay
  ENST00000463863 EIF2A-006 150546678-150558729 retained_intron
  ENST00000465535 EIF2A-015 150568032-150584234 protein_coding
  ENST00000469331 EIF2A-011 150546790-150562908 retained_intron
  ENST00000472926 EIF2A-014 150567399-150568219 retained_intron
  ENST00000473499 EIF2A-007 150546725-150552883 retained_intron
  ENST00000474505 EIF2A-009 150546786-150564899 retained_intron
  ENST00000477551 EIF2A-005 150552354-150584242 nonsense_mediated_decay
  ENST00000482093 EIF2A-010 150546788-150568026 protein_coding
  ENST00000482471 EIF2A-016 150572496-150583903 processed_transcript
  ENST00000487799 EIF2A-002 150546685-150584023 protein_coding
  ENST00000490505 EIF2A-012 150546800-150564377 nonsense_mediated_decay
  ENST00000494558 EIF2A-008 150546767-150568274 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaENST00000273435ENST00000406576ENST00000460851ENST00000465535ENST00000477551ENST00000482471ENST00000487799
Transcript ID Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000273435 N/A N/A 7.919±0.00 N/A N/A 6.083±0.00 N/A N/A N/A N/A N/A
ENST00000406576 N/A N/A N/A N/A 13.074±0.00 N/A N/A N/A 26.910±0.00 11.337±0.00 N/A
ENST00000460851 N/A N/A N/A 7.331±0.00 4.168±0.00 N/A 8.722±0.00 8.156±0.00 16.583±0.00 17.346±6.31 16.847±0.00
ENST00000465535 33.440±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000477551 N/A N/A N/A N/A N/A N/A N/A N/A 20.687±0.00 N/A N/A
ENST00000482471 N/A N/A N/A N/A N/A N/A N/A N/A N/A 74.143±0.00 88.570±0.00
ENST00000487799 N/A 2.543±0.00 N/A N/A 12.366±0.00 N/A N/A N/A 3.354±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002QY CIL_0002QY_0001 CGP 3:150408335-150603228
CIL_0004SR CIL_0004SR_0002 CGP 3:150541994-150603228
CIL_0002IA CIL_0002IA_0001 CGP 3:150546678-150630445

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000049 IMP tRNA binding
GO:0003743 IEA translation initiation factor activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0005850 IDA eukaryotic translation initiation factor 2 complex
GO:0006412 IEA translation
GO:0006413 IEA translational initiation
GO:0006417 IMP regulation of translation
GO:0006468 IEA protein phosphorylation
GO:0009967 IEA positive regulation of signal transduction
GO:0032933 IEA SREBP signaling pathway
GO:0042255 IMP ribosome assembly
GO:0043022 IMP ribosome binding
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044479 eif2a eukaryotic translation initiation factor 2A protein_coding Danio_rerio
ENSMUSG00000027810 Eif2a eukaryotic translation initiation factor 2A protein_coding Mus_musculus

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