C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 2A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027810 Eif2a 10090 + 3:58525821-58557501 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029387 Eif2a-001 58525821-58557501 protein_coding
  ENSMUST00000135876 Eif2a-002 58526043-58555644 nonsense_mediated_decay
  ENSMUST00000137469 Eif2a-004 58526042-58545823 retained_intron
  ENSMUST00000138827 Eif2a-005 58543280-58545823 retained_intron
  ENSMUST00000138848 Eif2a-007 58526303-58545611 protein_coding
  ENSMUST00000148251 Eif2a-006 58544233-58550726 retained_intron
  ENSMUST00000154219 Eif2a-003 58526056-58557501 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastHeartLiverMusclePlacentaENSMUST00000029387ENSMUST00000135876ENSMUST00000154219
Transcript ID Adipose Bladder Brain Breast Heart Liver Muscle Placenta
ENSMUST00000029387 5.083±0.15 18.698±0.18 12.724±0.57 8.745±0.00 5.005±1.30 22.498±5.00 12.767±1.10 18.759±6.41
ENSMUST00000135876 N/A N/A N/A N/A 3.436±0.16 N/A N/A N/A
ENSMUST00000154219 N/A N/A 4.612±0.00 N/A N/A N/A 3.281±0.59 9.671±1.24

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002QY CIL_0002QY_0002 CGP 3:58415689-58525873
CIL_0004SR CIL_0004SR_0003 CGP 3:58521969-58557501
CIL_0002IA CIL_0002IA_0002 CGP 3:58525821-58593133

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000049 ISS tRNA binding
GO:0003743 ISS translation initiation factor activity
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005737 ISS cytoplasm
GO:0005850 ISS eukaryotic translation initiation factor 2 complex
GO:0006412 IDA translation
GO:0006413 IEA translational initiation
GO:0006417 ISS regulation of translation
GO:0006468 IDA protein phosphorylation
GO:0009967 IDA positive regulation of signal transduction
GO:0032933 IDA SREBP signaling pathway
GO:0042255 ISS ribosome assembly
GO:0043022 ISS ribosome binding
GO:0072562 IEA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044479 eif2a eukaryotic translation initiation factor 2A protein_coding Danio_rerio
ENSG00000144895 EIF2A eukaryotic translation initiation factor 2A, 65kDa protein_coding Homo_sapiens

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