C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: eukaryotic translation initiation factor 2A, 65kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000460851 EIF2A-001 ENSG00000144895 9606 + 3:150546694-150584242 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartLiverLungMuscleOvaryPlacentaENST00000460851
Transcript ID Breast Heart Liver Lung Muscle Ovary Placenta
ENST00000460851 7.331±0.00 4.168±0.00 8.722±0.00 8.156±0.00 16.583±0.00 17.346±6.31 16.847±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002QY CIL_0002QY_0001 CGP 3:150408335-150603228
CIL_0004SR CIL_0004SR_0002 CGP 3:150541994-150603228
CIL_0002IA CIL_0002IA_0001 CGP 3:150546678-150630445

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000049 IMP tRNA binding
GO:0003743 IMP translation initiation factor activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0005850 IDA eukaryotic translation initiation factor 2 complex
GO:0006412 IEA translation
GO:0006413 IEA translational initiation
GO:0006417 IMP regulation of translation
GO:0006468 IEA protein phosphorylation
GO:0009967 IEA positive regulation of signal transduction
GO:0032933 IEA SREBP signaling pathway
GO:0042255 IMP ribosome assembly
GO:0043022 IMP ribosome binding
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000029387 Eif2a-001 protein_coding Mus_musculus 0 2385
ENSMUST00000154219 Eif2a-003 nonsense_mediated_decay Mus_musculus 0 1923
ENSMUST00000135876 Eif2a-002 nonsense_mediated_decay Mus_musculus 0 1725
ENSMUST00000148251 Eif2a-006 retained_intron Mus_musculus 0 1195
ENSMUST00000137469 Eif2a-004 retained_intron Mus_musculus 0 1075
ENSMUST00000138848 Eif2a-007 protein_coding Mus_musculus 0 1000
ENSMUST00000138827 Eif2a-005 retained_intron Mus_musculus 0 422

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