C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAS p21 protein activator (GTPase activating protein) 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000145715 RASA1 9606 + 5:87267888-87391931 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000274376 RASA1-001 87267888-87390927 protein_coding
  ENST00000456692 RASA1-002 87268933-87391931 protein_coding
  ENST00000506290 RASA1-003 87268944-87391129 protein_coding
  ENST00000509953 RASA1-007 87337972-87369901 retained_intron
  ENST00000512763 RASA1-004 87268944-87391099 protein_coding
  ENST00000515800 RASA1-005 87267888-87391919 nonsense_mediated_decay

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaENST00000274376ENST00000456692ENST00000512763ENST00000515800
Transcript ID Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta
ENST00000274376 2.727±0.00 6.177±0.00 N/A 3.039±0.00 3.619±0.00 4.447±0.00 3.307±0.00 N/A 2.749±0.07 N/A
ENST00000456692 N/A 4.771±0.00 3.278±0.00 N/A 4.381±0.00 1.308±0.00 3.903±0.00 1.132±0.15 3.859±0.94 12.470±4.96
ENST00000512763 N/A N/A N/A N/A 1.235±0.00 N/A N/A N/A N/A N/A
ENST00000515800 N/A N/A N/A N/A N/A 2.650±0.00 2.389±0.00 N/A 1.977±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005TN CIL_0005TN_0002 CGP 5:86617904-87391931
CIL_0005TO CIL_0005TO_0002 CGP 5:87267888-87413019

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000281 ISS mitotic cytokinesis
GO:0001570 ISS vasculogenesis
GO:0001726 IEA ruffle
GO:0001948 IPI glycoprotein binding
GO:0001953 IDA negative regulation of cell-matrix adhesion
GO:0005096 IEA GTPase activator activity
GO:0005099 IBA Ras GTPase activator activity
GO:0005102 IPI receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005737 IBA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0007162 IDA negative regulation of cell adhesion
GO:0007165 IDA:IEA signal transduction
GO:0008360 NAS regulation of cell shape
GO:0009790 ISS embryo development
GO:0019870 NAS potassium channel inhibitor activity
GO:0030833 IDA regulation of actin filament polymerization
GO:0031235 IBA intrinsic component of the cytoplasmic side of the plasma membrane
GO:0032318 IEA regulation of Ras GTPase activity
GO:0032320 IBA positive regulation of Ras GTPase activity
GO:0035556 NAS intracellular signal transduction
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0043547 IEA positive regulation of GTPase activity
GO:0046580 IBA negative regulation of Ras protein signal transduction
GO:0048514 IMP blood vessel morphogenesis
GO:0051020 IPI GTPase binding
GO:0051056 IEA regulation of small GTPase mediated signal transduction
GO:0051252 NAS regulation of RNA metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035535 rasa1a RAS p21 protein activator 1a protein_coding Danio_rerio
ENSDARG00000073665 rasa1b RAS p21 protein activator 1b protein_coding Danio_rerio
ENSMUSG00000021549 Rasa1 RAS p21 protein activator 1 protein_coding Mus_musculus

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