C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: RAS p21 protein activator (GTPase activating protein) 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000274376 RASA1-001 ENSG00000145715 9606 + 5:87267888-87390927 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainColonKidneyLiverLungOvaryENST00000274376
Transcript ID Bladder Brain Colon Kidney Liver Lung Ovary
ENST00000274376 2.727±0.00 6.177±0.00 3.039±0.00 3.619±0.00 4.447±0.00 3.307±0.00 2.749±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005TN CIL_0005TN_0002 CGP 5:86617904-87391931
CIL_0005TO CIL_0005TO_0002 CGP 5:87267888-87413019

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000281 ISS mitotic cytokinesis
GO:0001570 ISS vasculogenesis
GO:0001726 IEA ruffle
GO:0001948 IPI glycoprotein binding
GO:0001953 IDA negative regulation of cell-matrix adhesion
GO:0005099 IBA Ras GTPase activator activity
GO:0005102 IPI receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005737 IBA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0007162 IDA negative regulation of cell adhesion
GO:0007165 IDA:IEA signal transduction
GO:0008360 NAS regulation of cell shape
GO:0009790 ISS embryo development
GO:0019870 NAS potassium channel inhibitor activity
GO:0030833 IDA regulation of actin filament polymerization
GO:0031235 IBA intrinsic component of the cytoplasmic side of the plasma membrane
GO:0032318 IEA regulation of Ras GTPase activity
GO:0032320 IBA positive regulation of Ras GTPase activity
GO:0035556 NAS intracellular signal transduction
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0046580 IBA negative regulation of Ras protein signal transduction
GO:0048514 IMP blood vessel morphogenesis
GO:0051020 IPI GTPase binding
GO:0051252 NAS regulation of RNA metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000109552 Rasa1-001 protein_coding Mus_musculus 0 4364
ENSMUST00000148014 Rasa1-006 retained_intron Mus_musculus 0 904
ENSMUST00000142285 Rasa1-009 retained_intron Mus_musculus 0 697
ENSMUST00000146792 Rasa1-007 retained_intron Mus_musculus 0 448
ENSMUST00000152466 Rasa1-003 retained_intron Mus_musculus 0 440
ENSMUST00000149799 Rasa1-005 retained_intron Mus_musculus 0 424
ENSMUST00000153231 Rasa1-002 retained_intron Mus_musculus 0 327
ENSMUST00000141879 Rasa1-004 retained_intron Mus_musculus 0 246

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