C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: very low density lipoprotein receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147852 VLDLR 9606 + 9:2621834-2660053 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000382096 VLDLR-005 2621975-2643355 protein_coding
  ENST00000382099 VLDLR-002 2622100-2654480 protein_coding
  ENST00000382100 VLDLR-001 2621834-2660053 protein_coding
  ENST00000478776 VLDLR-004 2646338-2647768 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000382096ENST00000382099ENST00000382100
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000382096 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 16.879±0.00 14.116±0.00
ENST00000382099 4.760±0.00 2.133±0.00 1.284±0.00 3.241±0.06 7.504±5.30 1.712±0.54 13.261±10.40 3.372±2.73 2.107±1.79 4.586±3.64 4.358±1.14 15.740±16.54 6.757±1.22 6.352±0.25
ENST00000382100 0.866±0.00 0.508±0.00 N/A 0.312±0.06 1.909±1.45 0.433±0.00 3.077±2.08 0.718±0.00 0.426±0.33 0.908±0.37 N/A 3.026±3.63 1.369±0.81 1.030±0.70

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00051I CIL_00051I_0002 CGP 9:2621834-2730037

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001948 IPI glycoprotein binding
GO:0005041 TAS low-density lipoprotein receptor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005886 TAS plasma membrane
GO:0005905 IEA coated pit
GO:0006869 IEA lipid transport
GO:0006898 IDA receptor-mediated endocytosis
GO:0007165 TAS signal transduction
GO:0007399 TAS nervous system development
GO:0007613 TAS memory
GO:0008203 IEA cholesterol metabolic process
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0021517 IEA ventral spinal cord development
GO:0030229 IDA very-low-density lipoprotein particle receptor activity
GO:0034185 ISS apolipoprotein binding
GO:0034189 IDA very-low-density lipoprotein particle binding
GO:0034361 IEA very-low-density lipoprotein particle
GO:0034436 IDA glycoprotein transport
GO:0034437 IDA glycoprotein transporter activity
GO:0034447 IDA very-low-density lipoprotein particle clearance
GO:0038025 ISS reelin receptor activity
GO:0038026 ISS reelin-mediated signaling pathway
GO:0043235 IDA receptor complex
GO:0045860 IEA positive regulation of protein kinase activity
GO:0048306 IPI calcium-dependent protein binding
GO:1900006 ISS positive regulation of dendrite development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006257 vldlr very low density lipoprotein receptor protein_coding Danio_rerio
ENSMUSG00000024924 Vldlr very low density lipoprotein receptor protein_coding Mus_musculus

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