C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: very low density lipoprotein receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024924 Vldlr 10090 + 19:27216484-27254231 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025866 Vldlr-005 27217458-27249763 nonsense_mediated_decay
  ENSMUST00000047645 Vldlr-006 27217357-27249727 protein_coding
  ENSMUST00000163729 Vldlr-008 27217357-27231770 processed_transcript
  ENSMUST00000164509 Vldlr-003 27216484-27249755 retained_intron
  ENSMUST00000164746 Vldlr-007 27217020-27234856 protein_coding
  ENSMUST00000165761 Vldlr-009 27238774-27243828 protein_coding
  ENSMUST00000167487 Vldlr-001 27217357-27254231 protein_coding
  ENSMUST00000172302 Vldlr-002 27217020-27249862 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025866ENSMUST00000047645ENSMUST00000163729ENSMUST00000164509ENSMUST00000164746ENSMUST00000167487ENSMUST00000172302
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025866 11.256±0.48 N/A 2.247±0.37 N/A 4.460±0.90 N/A N/A 5.958±2.11 0.704±0.27 4.222±0.30 N/A 7.956±3.60 8.906±6.72 0.227±0.16
ENSMUST00000047645 4.906±0.20 N/A N/A N/A 3.835±1.88 N/A N/A N/A 1.115±0.16 N/A N/A N/A 1.755±0.05 0.086±0.05
ENSMUST00000163729 N/A 7.745±2.01 N/A N/A N/A N/A N/A N/A N/A N/A N/A 21.324±3.59 N/A N/A
ENSMUST00000164509 N/A 2.372±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000164746 N/A 6.699±0.81 N/A N/A N/A 3.853±0.45 N/A N/A 1.341±0.00 N/A N/A 50.370±59.57 108.347±9.28 N/A
ENSMUST00000167487 8.470±1.42 1.898±0.52 1.323±0.81 3.355±2.23 4.810±1.65 1.235±0.01 23.069±2.10 6.856±2.20 0.604±0.51 4.619±0.87 29.877±6.27 5.742±1.72 3.233±2.03 0.099±0.00
ENSMUST00000172302 8.105±1.05 4.412±0.85 1.494±0.35 N/A 4.853±1.53 2.646±0.33 17.097±1.99 6.577±2.37 0.736±0.25 4.327±1.15 N/A 11.590±2.19 N/A 0.053±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00051I CIL_00051I_0003 CGP 19:27216484-27337179

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001948 IEA glycoprotein binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005905 IEA coated pit
GO:0006869 IEA lipid transport
GO:0006898 IEA receptor-mediated endocytosis
GO:0008203 IEA cholesterol metabolic process
GO:0016020 ISO membrane
GO:0016021 IEA integral component of membrane
GO:0021517 IEP ventral spinal cord development
GO:0030229 ISS very-low-density lipoprotein particle receptor activity
GO:0034189 IEA very-low-density lipoprotein particle binding
GO:0034361 IEA very-low-density lipoprotein particle
GO:0034436 IEA glycoprotein transport
GO:0034437 IEA glycoprotein transporter activity
GO:0034447 ISS very-low-density lipoprotein particle clearance
GO:0038025 IGI reelin receptor activity
GO:0038026 IGI reelin-mediated signaling pathway
GO:0043235 ISO receptor complex
GO:0045860 IGI positive regulation of protein kinase activity
GO:0048306 IEA calcium-dependent protein binding
GO:1900006 IGI positive regulation of dendrite development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006257 vldlr very low density lipoprotein receptor protein_coding Danio_rerio
ENSG00000147852 VLDLR very low density lipoprotein receptor protein_coding Homo_sapiens

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