C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: gelsolin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148180 GSN 9606 + 9:121207794-121332843 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341272 GSN-201 121268102-121332842 protein_coding
  ENST00000373805 GSN-012 121326732-121329315 processed_transcript
  ENST00000373806 GSN-010 121326582-121332662 protein_coding
  ENST00000373807 GSN-005 121311471-121331890 protein_coding
  ENST00000373808 GSN-202 121268102-121332842 protein_coding
  ENST00000373818 GSN-001 121299793-121332842 protein_coding
  ENST00000373823 GSN-013 121207800-121332843 protein_coding
  ENST00000394353 GSN-203 121286081-121332842 protein_coding
  ENST00000412819 GSN-204 121268102-121332842 protein_coding
  ENST00000432226 GSN-002 121268060-121317112 protein_coding
  ENST00000434663 GSN-014 121207794-121265186 processed_transcript
  ENST00000436847 GSN-205 121268102-121332842 protein_coding
  ENST00000449733 GSN-206 121268102-121332842 protein_coding
  ENST00000449773 GSN-003 121268060-121312477 protein_coding
  ENST00000475428 GSN-004 121281511-121312489 processed_transcript
  ENST00000477104 GSN-006 121286123-121312495 processed_transcript
  ENST00000477553 GSN-008 121328853-121332589 processed_transcript
  ENST00000477863 GSN-007 121268163-121312475 processed_transcript
  ENST00000483960 GSN-009 121281472-121321311 processed_transcript
  ENST00000485767 GSN-011 121308371-121317886 processed_transcript
  ENST00000545652 GSN-207 121286580-121332842 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000341272ENST00000373806ENST00000373808ENST00000373818ENST00000394353ENST00000477863
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000341272 N/A N/A N/A 10.356±0.00 38.675±0.00 24.597±0.00 18.042±0.00 N/A 31.105±0.00 12.424±0.00 N/A N/A 54.915±4.10 N/A
ENST00000373806 N/A 206.920±0.00 N/A 91.816±0.00 526.379±0.00 503.218±0.00 N/A 68.862±0.00 9.464±0.00 170.750±0.00 N/A 134.072±0.00 198.742±0.00 188.287±26.14
ENST00000373808 N/A N/A 6.630±0.00 10.821±0.00 N/A 11.209±0.00 N/A 2.642±0.00 42.764±0.00 N/A 60.936±0.00 140.476±118.24 25.948±0.00 N/A
ENST00000373818 1278.430±0.00 301.425±0.00 6.922±0.00 97.437±0.00 543.820±488.54 423.315±395.74 210.050±177.92 108.620±0.00 66.837±56.62 172.969±151.86 212.972±0.00 160.533±103.30 59.657±33.95 192.003±139.99
ENST00000394353 N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.780±0.00 N/A N/A N/A N/A
ENST00000477863 N/A N/A N/A N/A N/A N/A N/A 4.152±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004FG CIL_0004FG_0001 CGP 9:121074863-121223014
CIL_0004FH CIL_0004FH_0001 CGP 9:121178137-121332843
CIL_0006N3 CIL_0006N3_0001 CGP 9:121207794-121370304

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 IEA ruffle
GO:0003779 IEA actin binding
GO:0005509 TAS calcium ion binding
GO:0005515 IPI protein binding
GO:0005576 ISS extracellular region
GO:0005615 IEA extracellular space
GO:0005829 ISS cytosol
GO:0005925 IDA focal adhesion
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0007568 IEA aging
GO:0008154 IEA actin polymerization or depolymerization
GO:0014003 IEA oligodendrocyte development
GO:0015629 IEA actin cytoskeleton
GO:0016192 IEA vesicle-mediated transport
GO:0030027 IEA lamellipodium
GO:0030041 ISS actin filament polymerization
GO:0030155 IEA regulation of cell adhesion
GO:0042060 IEA wound healing
GO:0042246 IEA tissue regeneration
GO:0043234 IEA protein complex
GO:0045471 IEA response to ethanol
GO:0048015 IEA phosphatidylinositol-mediated signaling
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051014 ISS actin filament severing
GO:0051016 TAS barbed-end actin filament capping
GO:0051593 IEA response to folic acid
GO:0060271 IMP cilium morphogenesis
GO:0070062 IDA extracellular vesicular exosome
GO:0071276 IEA cellular response to cadmium ion
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011459 gsna gelsolin a protein_coding Danio_rerio
ENSDARG00000045262 gsnb gelsolin b protein_coding Danio_rerio
ENSMUSG00000026879 Gsn gelsolin protein_coding Mus_musculus

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