C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: par-3 family cell polarity regulator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148498 PARD3 9606 - 10:34109560-34815325 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000340077 PARD3-201 34312260-34815325 protein_coding
  ENST00000346874 PARD3-004 34109561-34815321 protein_coding
  ENST00000350537 PARD3-006 34109561-34815321 protein_coding
  ENST00000374768 PARD3-007 34346198-34372533 protein_coding
  ENST00000374773 PARD3-009 34312264-34815321 protein_coding
  ENST00000374776 PARD3-001 34312256-34815321 protein_coding
  ENST00000374788 PARD3-003 34109561-34815321 protein_coding
  ENST00000374789 PARD3-002 34109561-34815321 protein_coding
  ENST00000374790 PARD3-010 34109561-34815321 protein_coding
  ENST00000374794 PARD3-005 34109561-34815321 protein_coding
  ENST00000466092 PARD3-008 34269787-34336320 processed_transcript
  ENST00000544292 PARD3-202 34312264-34426731 protein_coding
  ENST00000545260 PARD3-203 34109560-34815325 protein_coding
  ENST00000545693 PARD3-204 34109560-34815325 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000340077ENST00000346874ENST00000350537ENST00000374768ENST00000374773ENST00000374776ENST00000374788ENST00000374789ENST00000374790ENST00000374794ENST00000466092ENST00000544292ENST00000545260ENST00000545693
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000340077 N/A N/A N/A 0.706±0.00 N/A 5.377±0.00 N/A 2.440±0.00 2.515±0.00 N/A N/A 10.744±5.12 4.296±0.92 N/A
ENST00000346874 N/A N/A N/A N/A N/A N/A 1.216±0.00 N/A 0.811±0.00 N/A 5.504±0.00 N/A 5.832±0.00 9.116±0.00
ENST00000350537 0.843±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 3.018±1.86 N/A N/A N/A N/A
ENST00000374768 N/A N/A N/A 2.177±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000374773 1.722±0.00 N/A 3.327±0.00 1.131±0.00 N/A N/A N/A 2.362±0.92 2.783±0.00 N/A 8.593±0.00 N/A 4.204±1.08 N/A
ENST00000374776 N/A N/A N/A N/A N/A 5.020±0.00 N/A N/A N/A N/A N/A 2.635±0.00 N/A N/A
ENST00000374788 1.378±0.00 N/A N/A 0.157±0.00 1.667±0.00 N/A N/A 2.221±0.00 N/A N/A N/A N/A N/A N/A
ENST00000374789 0.946±0.00 N/A N/A 0.515±0.00 1.261±0.00 3.294±0.00 N/A 1.620±0.00 N/A N/A N/A 3.210±0.12 1.820±0.28 3.504±0.00
ENST00000374790 N/A 1.435±0.00 N/A N/A N/A N/A N/A 1.483±0.00 N/A N/A N/A 3.964±0.00 N/A N/A
ENST00000374794 1.088±0.00 N/A N/A N/A 2.325±0.00 4.470±0.00 N/A N/A N/A 2.630±0.00 6.057±0.00 5.912±0.00 5.420±0.00 4.307±0.00
ENST00000466092 N/A N/A N/A 3.181±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000544292 1.838±0.00 N/A N/A N/A 2.105±0.00 N/A N/A N/A 1.982±0.00 N/A N/A 10.500±0.00 N/A N/A
ENST00000545260 N/A N/A N/A 0.515±0.00 3.153±0.00 N/A 0.944±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000545693 N/A N/A 0.972±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 2.317±0.98 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000226 IEA microtubule cytoskeleton organization
GO:0003383 IEA apical constriction
GO:0005080 IEA protein kinase C binding
GO:0005515 IPI:IEA protein binding
GO:0005546 ISS phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 ISS phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005737 IEA cytoplasm
GO:0005819 IEA spindle
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005911 ISS cell-cell junction
GO:0005912 IEA adherens junction
GO:0005913 IEA cell-cell adherens junction
GO:0005923 ISS tight junction
GO:0005938 IEA cell cortex
GO:0006461 TAS protein complex assembly
GO:0006612 ISS protein targeting to membrane
GO:0007049 IEA cell cycle
GO:0007163 TAS establishment or maintenance of cell polarity
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007205 TAS protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007409 TAS axonogenesis
GO:0008356 TAS asymmetric cell division
GO:0010801 ISS negative regulation of peptidyl-threonine phosphorylation
GO:0019903 IEA protein phosphatase binding
GO:0022011 ISS myelination in peripheral nervous system
GO:0030054 IDA cell junction
GO:0031643 ISS positive regulation of myelination
GO:0032266 ISS phosphatidylinositol-3-phosphate binding
GO:0032970 IEA regulation of actin filament-based process
GO:0033269 ISS internode region of axon
GO:0034329 TAS cell junction assembly
GO:0043025 IEA neuronal cell body
GO:0043234 IEA protein complex
GO:0044295 IEA axonal growth cone
GO:0044319 IEA wound healing, spreading of cells
GO:0045177 IEA apical part of cell
GO:0045216 TAS cell-cell junction organization
GO:0051642 IEA centrosome localization
GO:0060341 IEA regulation of cellular localization
GO:0070830 ISS tight junction assembly
GO:0090162 ISS establishment of epithelial cell polarity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010583 pard3 par-3 partitioning defective 3 homolog (C. elegans) protein_coding Danio_rerio
ENSDARG00000091238 CABZ01071446.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000025812 Pard3 par-3 family cell polarity regulator protein_coding Mus_musculus

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