C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: par-3 family cell polarity regulator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025812 Pard3 10090 + 8:127063893-127612286 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026921 Pard3-006 127064295-127610805 protein_coding
  ENSMUST00000079777 Pard3-201 127064056-127432825 protein_coding
  ENSMUST00000108752 Pard3-202 127306310-127402059 protein_coding
  ENSMUST00000159141 Pard3-020 127064259-127277105 nonsense_mediated_decay
  ENSMUST00000159511 Pard3-025 127447746-127474513 protein_coding
  ENSMUST00000159537 Pard3-012 127064347-127426684 protein_coding
  ENSMUST00000159818 Pard3-021 127064259-127370372 nonsense_mediated_decay
  ENSMUST00000159940 Pard3-026 127579724-127610848 processed_transcript
  ENSMUST00000160272 Pard3-002 127064056-127612286 protein_coding
  ENSMUST00000160581 Pard3-017 127064345-127426753 protein_coding
  ENSMUST00000160593 Pard3-005 127064098-127412201 retained_intron
  ENSMUST00000160717 Pard3-004 127299585-127402577 protein_coding
  ENSMUST00000160766 Pard3-014 127064345-127611970 protein_coding
  ENSMUST00000161277 Pard3-013 127073240-127426684 protein_coding
  ENSMUST00000161348 Pard3-009 127405445-127433141 protein_coding
  ENSMUST00000161355 Pard3-019 127064345-127426753 protein_coding
  ENSMUST00000162035 Pard3-010 127356415-127361791 retained_intron
  ENSMUST00000162176 Pard3-011 127357311-127398632 protein_coding
  ENSMUST00000162309 Pard3-001 127063893-127611970 protein_coding
  ENSMUST00000162456 Pard3-007 127299612-127433144 protein_coding
  ENSMUST00000162531 Pard3-016 127064345-127474606 protein_coding
  ENSMUST00000162536 Pard3-018 127064245-127611970 protein_coding
  ENSMUST00000162602 Pard3-015 127064345-127426753 protein_coding
  ENSMUST00000162665 Pard3-008 127064295-127610805 protein_coding
  ENSMUST00000162727 Pard3-023 127389317-127400677 protein_coding
  ENSMUST00000162907 Pard3-003 127064070-127402577 protein_coding
  ENSMUST00000163002 Pard3-024 127410649-127474497 retained_intron
  ENSMUST00000163021 Pard3-022 127371490-127376968 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026921ENSMUST00000079777ENSMUST00000108752ENSMUST00000159537ENSMUST00000160272ENSMUST00000160581ENSMUST00000160766ENSMUST00000161277ENSMUST00000161355ENSMUST00000162176ENSMUST00000162309ENSMUST00000162536ENSMUST00000162602ENSMUST00000162665ENSMUST00000162907ENSMUST00000163002ENSMUST00000163021
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026921 0.957±0.00 N/A N/A N/A 1.794±0.00 N/A 1.509±0.34 N/A N/A 2.121±0.00 1.746±0.62 4.901±0.00 N/A 0.864±0.31
ENSMUST00000079777 N/A N/A N/A 2.161±0.00 N/A 3.822±1.09 N/A 3.580±1.16 3.288±2.00 N/A N/A 5.985±0.00 N/A 0.340±0.00
ENSMUST00000108752 N/A N/A N/A N/A 2.464±0.00 N/A 1.227±0.22 N/A N/A N/A 1.565±0.00 N/A 8.605±0.71 N/A
ENSMUST00000159537 N/A N/A N/A N/A N/A N/A 1.761±0.20 N/A 2.573±0.00 N/A N/A N/A N/A N/A
ENSMUST00000160272 1.764±0.64 3.240±0.00 2.921±0.82 3.832±1.00 1.119±0.20 2.179±0.00 1.402±0.32 2.773±0.47 1.428±0.64 N/A 1.611±0.28 N/A 3.776±0.90 0.254±0.07
ENSMUST00000160581 N/A N/A N/A N/A N/A N/A 1.465±0.00 3.492±0.00 1.726±0.79 N/A N/A N/A N/A N/A
ENSMUST00000160766 N/A N/A N/A N/A 1.147±0.00 N/A N/A N/A 1.790±0.00 N/A N/A 2.900±0.00 4.763±0.00 N/A
ENSMUST00000161277 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.347±0.00
ENSMUST00000161355 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.850±0.20 N/A N/A N/A
ENSMUST00000162176 N/A N/A N/A 7.503±0.00 N/A N/A N/A N/A N/A N/A N/A 18.657±0.00 41.570±10.23 N/A
ENSMUST00000162309 2.488±1.20 4.175±0.57 2.364±0.31 1.955±0.58 3.210±0.41 2.735±0.56 0.620±0.00 1.916±0.32 0.667±0.03 6.378±1.42 1.325±0.38 5.615±1.63 5.514±2.74 0.299±0.05
ENSMUST00000162536 N/A N/A N/A N/A 1.958±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000162602 1.428±0.00 N/A N/A N/A N/A N/A 1.237±0.00 2.873±0.00 2.121±0.00 N/A 2.356±0.47 N/A N/A 0.326±0.06
ENSMUST00000162665 N/A N/A N/A N/A N/A N/A N/A 2.954±0.82 1.151±0.00 N/A N/A N/A N/A 0.289±0.00
ENSMUST00000162907 2.541±0.65 N/A 4.658±0.34 3.450±0.54 2.096±0.91 3.064±0.28 1.000±0.00 2.232±0.64 2.276±1.00 4.754±1.20 1.800±0.32 N/A 5.641±1.47 N/A
ENSMUST00000163002 N/A N/A N/A 4.858±0.00 N/A N/A N/A N/A N/A N/A N/A 22.857±0.00 N/A 12.033±0.00
ENSMUST00000163021 N/A 18.549±0.94 N/A N/A N/A 15.086±3.47 N/A 14.152±0.83 19.276±4.10 N/A N/A 22.270±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000CM CIL_0000CM_0002 CGP 8:127063893-128505462

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000226 IMP microtubule cytoskeleton organization
GO:0003383 IGI apical constriction
GO:0005080 IPI protein kinase C binding
GO:0005515 IPI protein binding
GO:0005546 ISS phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 ISS phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005737 IDA cytoplasm
GO:0005819 IDA spindle
GO:0005886 IEA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005912 IDA adherens junction
GO:0005913 IDA cell-cell adherens junction
GO:0005923 ISS tight junction
GO:0005938 IDA cell cortex
GO:0006612 ISS protein targeting to membrane
GO:0007049 IEA cell cycle
GO:0007163 TAS establishment or maintenance of cell polarity
GO:0010801 IMP negative regulation of peptidyl-threonine phosphorylation
GO:0016337 IC single organismal cell-cell adhesion
GO:0019903 IEA protein phosphatase binding
GO:0022011 IMP myelination in peripheral nervous system
GO:0030054 IDA cell junction
GO:0031643 IMP positive regulation of myelination
GO:0032266 ISS phosphatidylinositol-3-phosphate binding
GO:0032970 IGI regulation of actin filament-based process
GO:0033269 IDA internode region of axon
GO:0043025 IEA neuronal cell body
GO:0043219 IDA lateral loop
GO:0043220 IDA Schmidt-Lanterman incisure
GO:0043234 IDA protein complex
GO:0044295 IEA axonal growth cone
GO:0044319 IMP wound healing, spreading of cells
GO:0045177 IDA apical part of cell
GO:0051301 IEA cell division
GO:0051642 IMP centrosome localization
GO:0060341 IEA regulation of cellular localization
GO:0070830 ISS tight junction assembly
GO:0090162 ISS establishment of epithelial cell polarity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010583 pard3 par-3 partitioning defective 3 homolog (C. elegans) protein_coding Danio_rerio
ENSDARG00000091238 CABZ01071446.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000148498 PARD3 par-3 family cell polarity regulator protein_coding Homo_sapiens

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