C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148680 HTR7 9606 - 10:90740823-90857698 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000277874 HTR7-002 90740823-90857698 protein_coding
  ENST00000336152 HTR7-001 90740823-90857698 protein_coding
  ENST00000371719 HTR7-003 90740823-90857698 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000277874ENST00000336152ENST00000371719
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000277874 0.053±0.00 0.174±0.00 0.027±0.00 0.113±0.03 0.113±0.00 0.211±0.11 0.070±0.00 0.101±0.00 0.045±0.00 0.063±0.00 0.106±0.03 0.098±0.07 2.853±0.27
ENST00000336152 N/A N/A N/A 0.608±0.00 0.403±0.00 N/A 0.024±0.00 N/A 0.620±0.00 N/A 0.089±0.00 0.102±0.00 3.075±0.97
ENST00000371719 N/A N/A 0.028±0.00 N/A N/A N/A N/A N/A 0.005±0.00 0.599±0.00 0.142±0.00 0.120±0.00 5.273±4.50

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005PF CIL_0005PF_0002 CGP 10:89701610-90857698
CIL_0008BY CIL_0008BY_0001 VISTA 10:90630264-91230917
CIL_0005UK CIL_0005UK_0001 CGP 10:90740823-90908553

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0004993 IEA serotonin receptor activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006939 IEA smooth muscle contraction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007187 TAS G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007210 IEA serotonin receptor signaling pathway
GO:0007268 IEA synaptic transmission
GO:0007623 IEA circadian rhythm
GO:0008015 TAS blood circulation
GO:0016021 IEA integral component of membrane
GO:0042310 IEA vasoconstriction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056949 HTR7 (1 of 2) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled protein_coding Danio_rerio
ENSDARG00000089287 HTR7 (2 of 2) 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled protein_coding Danio_rerio
ENSMUSG00000024798 Htr7 5-hydroxytryptamine (serotonin) receptor 7 protein_coding Mus_musculus

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