C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000277874 HTR7-002 ENSG00000148680 9606 - 10:90740823-90857698 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000277874
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000277874 0.053±0.00 0.174±0.00 0.027±0.00 0.113±0.03 0.113±0.00 0.211±0.11 0.070±0.00 0.101±0.00 0.045±0.00 0.063±0.00 0.106±0.03 0.098±0.07 2.853±0.27

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005PF CIL_0005PF_0002 CGP 10:89701610-90857698
CIL_0008BY CIL_0008BY_0001 VISTA 10:90630264-91230917
CIL_0005UK CIL_0005UK_0001 CGP 10:90740823-90908553

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0004993 IEA serotonin receptor activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006939 IEA smooth muscle contraction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007187 TAS G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007210 IEA serotonin receptor signaling pathway
GO:0007268 IEA synaptic transmission
GO:0007623 IEA circadian rhythm
GO:0008015 TAS blood circulation
GO:0016021 IEA integral component of membrane
GO:0042310 IEA vasoconstriction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000164639 Htr7-001 protein_coding Mus_musculus 0 2420
ENSMUST00000166074 Htr7-005 protein_coding Mus_musculus 0 2390
ENSMUST00000099505 Htr7-006 protein_coding Mus_musculus 0 1744
ENSMUST00000165215 Htr7-002 nonsense_mediated_decay Mus_musculus 0 1668
ENSMUST00000164781 Htr7-004 nonsense_mediated_decay Mus_musculus 0 1646
ENSMUST00000170360 Htr7-003 nonsense_mediated_decay Mus_musculus 0 1020

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