C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: programmed cell death 4 (neoplastic transformation inhibitor)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000150593 PDCD4 9606 + 10:110871795-110900006 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000280154 PDCD4-001 110871807-110900006 protein_coding
  ENST00000393104 PDCD4-201 110871795-110900005 protein_coding
  ENST00000444997 PDCD4-004 110871955-110887844 protein_coding
  ENST00000462577 PDCD4-006 110885253-110898122 processed_transcript
  ENST00000467574 PDCD4-002 110871893-110887761 processed_transcript
  ENST00000481353 PDCD4-007 110884771-110894179 processed_transcript
  ENST00000483595 PDCD4-009 110887773-110896043 processed_transcript
  ENST00000483670 PDCD4-003 110871919-110885339 processed_transcript
  ENST00000489049 PDCD4-008 110887753-110890870 processed_transcript
  ENST00000492932 PDCD4-005 110880319-110887798 processed_transcript
  ENST00000498367 PDCD4-010 110890638-110898718 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000280154ENST00000444997ENST00000462577ENST00000481353ENST00000483595ENST00000492932ENST00000498367
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000280154 N/A N/A 2.065±0.00 N/A 5.957±0.00 N/A 1.262±0.00 N/A 2.482±0.00 N/A 5.897±1.30 N/A N/A
ENST00000444997 39.310±0.00 N/A N/A 33.006±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000462577 26.202±0.00 N/A N/A 29.626±0.00 N/A N/A N/A N/A N/A N/A 62.536±16.75 48.563±30.21 48.659±10.04
ENST00000481353 N/A N/A N/A N/A N/A N/A N/A 19.416±0.00 N/A N/A 20.941±0.00 N/A N/A
ENST00000483595 44.519±0.00 N/A N/A 45.942±0.00 41.909±0.00 19.735±0.00 N/A N/A N/A N/A 123.130±0.00 130.623±0.00 57.207±0.00
ENST00000492932 N/A N/A N/A N/A 28.522±0.00 3.940±0.00 N/A 31.020±0.00 20.464±0.00 N/A 24.111±0.00 N/A N/A
ENST00000498367 33.112±0.00 77.171±0.00 16.363±7.73 37.149±0.00 30.368±3.24 N/A 8.147±0.00 21.099±0.00 17.968±1.31 6.578±0.00 59.966±45.71 72.182±59.11 55.726±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008Q9 CIL_0008Q9_0001 VISTA 10:110384599-110985964
CIL_0000UM CIL_0000UM_0001 CGP 10:110644397-110900006

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003723 IEA RNA binding
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IMP cytoplasm
GO:0005829 IDA cytosol
GO:0006915 NAS apoptotic process
GO:0007569 IDA cell aging
GO:0043508 ISS negative regulation of JUN kinase activity
GO:0045786 NAS negative regulation of cell cycle
GO:0045892 ISS negative regulation of transcription, DNA-templated

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041022 pdcd4b programmed cell death 4b protein_coding Danio_rerio
ENSMUSG00000024975 Pdcd4 programmed cell death 4 protein_coding Mus_musculus

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