C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: acyl-CoA synthetase long-chain family member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000151726 ACSL1 9606 - 4:184755595-184826818 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000281455 ACSL1-001 184755601-184826094 protein_coding
  ENST00000454703 ACSL1-005 184755595-184826119 protein_coding
  ENST00000503407 ACSL1-009 184755601-184766702 protein_coding
  ENST00000504342 ACSL1-002 184757021-184812259 protein_coding
  ENST00000504900 ACSL1-004 184768030-184826052 protein_coding
  ENST00000505492 ACSL1-008 184768328-184773873 protein_coding
  ENST00000506733 ACSL1-003 184756903-184808451 nonsense_mediated_decay
  ENST00000507295 ACSL1-006 184756781-184826034 protein_coding
  ENST00000513001 ACSL1-010 184755600-184758876 retained_intron
  ENST00000513317 ACSL1-007 184757047-184805788 protein_coding
  ENST00000515030 ACSL1-011 184755600-184826818 protein_coding
  ENST00000622937 ACSL1-201 184755596-184808601 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000281455ENST00000454703ENST00000503407ENST00000504342ENST00000507295ENST00000513317
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000281455 98.619±0.00 3.997±0.00 1.897±0.00 8.179±0.00 119.664±115.71 5.748±2.52 47.374±39.87 45.710±11.61 121.064±111.83 12.786±0.00 38.921±32.32 4.134±2.29 3.750±1.30 4.671±0.00
ENST00000454703 N/A 2.524±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.472±0.00 3.567±1.50 N/A
ENST00000503407 85.137±0.00 5.897±0.00 N/A 17.799±0.00 131.340±0.00 9.476±0.00 12.318±6.88 74.793±0.00 238.753±0.00 15.290±0.00 12.289±0.00 5.428±1.63 2.506±0.00 15.693±0.00
ENST00000504342 N/A N/A 5.078±0.00 1.414±0.00 5.174±0.00 4.642±0.00 10.409±0.00 47.548±0.00 9.856±0.00 6.439±0.00 20.805±0.00 2.701±0.00 N/A 33.552±18.49
ENST00000507295 N/A N/A N/A 4.557±3.63 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000513317 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.025±0.00 3.638±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000Z8 CIL_0000Z8_0002 CGP 4:184755595-185020804

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001676 IDA long-chain fatty acid metabolic process
GO:0003824 IEA catalytic activity
GO:0004467 IDA long-chain fatty acid-CoA ligase activity
GO:0005524 IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0005741 TAS mitochondrial outer membrane
GO:0005778 IEA peroxisomal membrane
GO:0005783 IEA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005886 IEA plasma membrane
GO:0006631 IEA fatty acid metabolic process
GO:0006641 IEA triglyceride metabolic process
GO:0007584 IEA response to nutrient
GO:0008152 IEA metabolic process
GO:0008610 IDA lipid biosynthetic process
GO:0010033 IEA response to organic substance
GO:0014070 IEA response to organic cyclic compound
GO:0015908 IEA fatty acid transport
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0019432 TAS triglyceride biosynthetic process
GO:0033211 IEA adiponectin-activated signaling pathway
GO:0033559 TAS unsaturated fatty acid metabolic process
GO:0034201 IEA response to oleic acid
GO:0035338 TAS long-chain fatty-acyl-CoA biosynthetic process
GO:0036109 TAS alpha-linolenic acid metabolic process
GO:0042178 IEA xenobiotic catabolic process
GO:0042493 IEA response to drug
GO:0043651 TAS linoleic acid metabolic process
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0044539 IDA long-chain fatty acid import
GO:0071902 IEA positive regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003854 acsl1b acyl-CoA synthetase long-chain family member 1b protein_coding Danio_rerio
ENSDARG00000030514 acsl1a acyl-CoA synthetase long-chain family member 1a protein_coding Danio_rerio
ENSMUSG00000018796 Acsl1 acyl-CoA synthetase long-chain family member 1 protein_coding Mus_musculus

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