C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, delta 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152208 GRID2 9606 + 4:92304399-93774556 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000282020 GRID2-001 92304399-93774556 protein_coding
  ENST00000502699 GRID2-006 92822949-93166161 nonsense_mediated_decay
  ENST00000505687 GRID2-003 92304485-93217267 processed_transcript
  ENST00000510992 GRID2-002 92304657-93772498 protein_coding
  ENST00000512631 GRID2-005 93203949-93238421 protein_coding
  ENST00000513976 GRID2-007 93238371-93306322 nonsense_mediated_decay
  ENST00000515744 GRID2-004 92822949-93112247 processed_transcript
  ENST00000611049 GRID2-201 93084986-93774553 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000282020ENST00000502699ENST00000505687ENST00000510992ENST00000512631ENST00000611049
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000282020 N/A 0.552±0.00 N/A 0.061±0.00 0.011±0.00 N/A N/A N/A 0.106±0.06 N/A N/A
ENST00000502699 N/A N/A N/A N/A 0.159±0.00 N/A 0.269±0.00 N/A N/A N/A N/A
ENST00000505687 N/A N/A N/A N/A 0.035±0.00 N/A N/A N/A N/A N/A N/A
ENST00000510992 N/A 0.719±0.34 0.030±0.00 0.027±0.00 0.039±0.00 0.029±0.00 0.214±0.00 0.135±0.00 N/A 0.036±0.02 1.472±0.37
ENST00000512631 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.903±5.11
ENST00000611049 0.007±0.00 N/A N/A N/A N/A 0.021±0.00 0.068±0.00 0.032±0.00 0.235±0.19 0.015±0.00 0.424±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001RV CIL_0001RV_0002 CGP 4:90127535-93774556
CIL_0005BW CIL_0005BW_0002 CGP 4:92304399-93830964

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004970 IBA:IEA ionotropic glutamate receptor activity
GO:0005234 IBA:IEA extracellular-glutamate-gated ion channel activity
GO:0005515 IEA protein binding
GO:0005886 ISS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006810 TAS transport
GO:0007157 ISS heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007215 TAS glutamate receptor signaling pathway
GO:0008066 TAS glutamate receptor activity
GO:0008328 ISS ionotropic glutamate receptor complex
GO:0010975 IEA regulation of neuron projection development
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0021707 ISS cerebellar granule cell differentiation
GO:0030054 IEA cell junction
GO:0030165 ISS PDZ domain binding
GO:0030425 IBA dendrite
GO:0034220 IBA ion transmembrane transport
GO:0034613 ISS cellular protein localization
GO:0035235 IBA ionotropic glutamate receptor signaling pathway
GO:0035249 ISS synaptic transmission, glutamatergic
GO:0043197 ISS dendritic spine
GO:0043523 ISS regulation of neuron apoptotic process
GO:0045202 ISS synapse
GO:0045211 IBA postsynaptic membrane
GO:0060079 ISS regulation of excitatory postsynaptic membrane potential
GO:0060134 ISS prepulse inhibition
GO:0097110 ISS scaffold protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055302 grid2 glutamate receptor, ionotropic, delta 2 protein_coding Danio_rerio
ENSMUSG00000071424 Grid2 glutamate receptor, ionotropic, delta 2 protein_coding Mus_musculus

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