C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SPC25, NDC80 kinetochore complex component
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152253 SPC25 9606 - 2:168834132-168913371 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000282074 SPC25-001 168870894-168890445 protein_coding
  ENST00000451987 SPC25-004 168877238-168913277 protein_coding
  ENST00000472216 SPC25-003 168877238-168913371 processed_transcript
  ENST00000479309 SPC25-002 168834132-168889293 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000282074ENST00000451987ENST00000479309
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000282074 0.115±0.00 0.321±0.00 0.108±0.00 0.300±0.00 0.741±0.01 0.245±0.01 0.081±0.00 0.130±0.00 0.052±0.02 0.243±0.12 0.014±0.00 6.092±6.06 2.302±1.05 2.687±0.76
ENST00000451987 N/A N/A N/A 0.931±0.00 N/A N/A N/A N/A 0.124±0.00 N/A 0.084±0.00 N/A N/A N/A
ENST00000479309 0.171±0.00 N/A N/A 0.340±0.00 N/A N/A N/A 0.556±0.00 N/A 0.181±0.00 N/A N/A N/A 1.665±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00063C CIL_00063C_0001 CGP 2:168455862-168865514
CIL_000639 CIL_000639_0001 CGP 2:168786539-168913371
CIL_0008HC CIL_0008HC_0001 VISTA 2:168815051-169417863
CIL_00063A CIL_00063A_0001 CGP 2:168834132-168913371

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000278 TAS mitotic cell cycle
GO:0000777 IDA condensed chromosome kinetochore
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0007052 IMP mitotic spindle organization
GO:0007059 IMP chromosome segregation
GO:0007067 IEA mitotic nuclear division
GO:0031262 IDA Ndc80 complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078433 spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000005233 Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) protein_coding Mus_musculus

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