C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005233 Spc25 10090 - 2:69193895-69206194 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005365 Spc25-001 69193895-69206194 protein_coding
  ENSMUST00000112320 Spc25-003 69193895-69206135 protein_coding
  ENSMUST00000126638 Spc25-004 69198647-69206123 processed_transcript
  ENSMUST00000127243 Spc25-002 69193895-69206157 protein_coding
  ENSMUST00000149045 Spc25-008 69197147-69205130 protein_coding
  ENSMUST00000149401 Spc25-007 69199923-69205215 processed_transcript
  ENSMUST00000149643 Spc25-005 69197190-69206180 protein_coding
  ENSMUST00000150505 Spc25-006 69205638-69206179 processed_transcript
  ENSMUST00000167875 Spc25-201 69193896-69206190 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005365ENSMUST00000112320ENSMUST00000126638ENSMUST00000127243ENSMUST00000149045ENSMUST00000149401ENSMUST00000149643ENSMUST00000150505
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005365 0.459±0.21 N/A 0.891±0.19 8.921±3.76 0.162±0.00 0.444±0.26 0.145±0.00 2.175±0.77 20.166±22.43 N/A 0.160±0.07 2.081±0.68 17.054±11.81 3.226±0.93
ENSMUST00000112320 0.745±0.44 0.385±0.12 0.374±0.02 3.081±0.56 0.319±0.19 0.762±0.31 0.111±0.02 4.401±0.63 7.059±7.52 0.274±0.00 N/A 1.437±0.69 8.557±0.59 0.866±0.07
ENSMUST00000126638 0.171±0.11 N/A 0.143±0.00 N/A 0.109±0.05 0.515±0.28 0.052±0.04 N/A 0.218±0.06 0.674±0.16 0.024±0.00 0.314±0.12 0.291±0.00 N/A
ENSMUST00000127243 N/A N/A N/A N/A 0.446±0.00 N/A 0.119±0.05 N/A 0.346±0.00 N/A 0.108±0.03 2.393±1.23 0.751±0.00 N/A
ENSMUST00000149045 N/A N/A N/A N/A N/A 0.504±0.00 N/A N/A N/A N/A 0.118±0.00 N/A 4.584±0.00 N/A
ENSMUST00000149401 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.264±0.06 27.812±0.00 40.706±33.61 35.244±0.00
ENSMUST00000149643 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.619±0.00 N/A N/A
ENSMUST00000150505 N/A N/A N/A N/A N/A N/A N/A N/A 0.668±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HC CIL_0008HC_0002 VISTA 2:69119794-69721610
CIL_000639 CIL_000639_0002 CGP 2:69135800-69206194
CIL_00063A CIL_00063A_0002 CGP 2:69193895-69227841

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000777 ISS condensed chromosome kinetochore
GO:0003674 ND molecular_function
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0007052 ISS mitotic spindle organization
GO:0007059 ISS chromosome segregation
GO:0007067 IEA mitotic nuclear division
GO:0031262 ISS Ndc80 complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078433 spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) protein_coding Danio_rerio
ENSG00000152253 SPC25 SPC25, NDC80 kinetochore complex component protein_coding Homo_sapiens

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