C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phospholipase A2 receptor 1, 180kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000392771 PLA2R1-002 ENSG00000153246 9606 - 2:159945815-160062610 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000392771
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000392771 0.511±0.00 0.324±0.00 1.357±0.00 0.075±0.01 0.812±0.10 0.710±0.09 0.172±0.04 3.505±0.00 2.358±0.00 0.493±0.28 0.151±0.00 1.256±0.63 0.569±0.35 0.305±0.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005TY CIL_0005TY_0001 CGP 2:159803355-160062610
CIL_0005TX CIL_0005TX_0001 CGP 2:159932006-160271888

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001816 IMP cytokine production
GO:0004872 IDA receptor activity
GO:0005576 ISS extracellular region
GO:0005886 IDA plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006898 IDA receptor-mediated endocytosis
GO:0009986 IDA cell surface
GO:0016021 IEA integral component of membrane
GO:0030246 IEA carbohydrate binding
GO:0043235 IDA receptor complex
GO:0043274 IPI phospholipase binding
GO:0043517 IMP positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0070062 IDA extracellular vesicular exosome
GO:0072593 IDA reactive oxygen species metabolic process
GO:0090238 ISS positive regulation of arachidonic acid secretion
GO:0090399 IMP replicative senescence
GO:0090403 IMP oxidative stress-induced premature senescence
GO:1900138 ISS negative regulation of phospholipase A2 activity
GO:1900139 ISS negative regulation of arachidonic acid secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000112525 Pla2r1-001 protein_coding Mus_musculus 0 3081
ENSMUST00000067708 Pla2r1-201 protein_coding Mus_musculus 0 3081
ENSMUST00000128208 Pla2r1-002 processed_transcript Mus_musculus 0 1417
ENSMUST00000134583 Pla2r1-005 processed_transcript Mus_musculus 0 263

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