C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysophosphatidylcholine acyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000153395 LPCAT1 9606 - 5:1456480-1523977 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000283415 LPCAT1-002 1461423-1523977 protein_coding
  ENST00000475622 LPCAT1-001 1456480-1523962 nonsense_mediated_decay
  ENST00000503252 LPCAT1-003 1461429-1467325 processed_transcript
  ENST00000507282 LPCAT1-006 1488377-1494928 retained_intron
  ENST00000513757 LPCAT1-008 1479476-1494778 retained_intron
  ENST00000514484 LPCAT1-004 1483428-1523740 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000283415ENST00000503252
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000283415 2.069±0.00 9.710±0.00 1.158±0.00 5.292±1.98 3.745±3.03 4.991±4.12 1.976±1.64 5.726±5.34 1.990±0.21 17.449±2.98 0.512±0.29 11.930±6.16 19.029±5.14 4.463±3.14
ENST00000503252 1.598±0.00 8.186±0.00 N/A N/A 1.477±0.00 1.557±0.00 0.181±0.00 1.214±0.46 N/A 13.921±0.00 0.370±0.00 8.767±4.00 3.997±0.21 2.947±1.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006VY CIL_0006VY_0002 CGP 5:1392790-1523977

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005509 IEA calcium ion binding
GO:0005783 ISS endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005794 ISS Golgi apparatus
GO:0005811 IDA lipid particle
GO:0006644 TAS phospholipid metabolic process
GO:0006654 TAS phosphatidic acid biosynthetic process
GO:0008152 IEA metabolic process
GO:0008654 ISS phospholipid biosynthetic process
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016746 IEA transferase activity, transferring acyl groups
GO:0019432 TAS triglyceride biosynthetic process
GO:0036148 TAS phosphatidylglycerol acyl-chain remodeling
GO:0036151 IDA phosphatidylcholine acyl-chain remodeling
GO:0043129 IEA surfactant homeostasis
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045732 IEA positive regulation of protein catabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0047159 IEA 1-alkenylglycerophosphocholine O-acyltransferase activity
GO:0047184 ISS 1-acylglycerophosphocholine O-acyltransferase activity
GO:0047191 IEA 1-alkylglycerophosphocholine O-acyltransferase activity
GO:0047192 IEA 1-alkylglycerophosphocholine O-acetyltransferase activity
GO:0060041 IEA retina development in camera-type eye
GO:2001246 IEA negative regulation of phosphatidylcholine biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011506 lpcat1 lysophosphatidylcholine acyltransferase 1 protein_coding Danio_rerio
ENSDARG00000077671 CABZ01078889.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000021608 Lpcat1 lysophosphatidylcholine acyltransferase 1 protein_coding Mus_musculus

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