C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysophosphatidylcholine acyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021608 Lpcat1 10090 + 13:73467197-73516422 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022099 Lpcat1-001 73467197-73516422 protein_coding
  ENSMUST00000123766 Lpcat1-003 73467197-73516422 nonsense_mediated_decay
  ENSMUST00000124627 Lpcat1-006 73510949-73511606 retained_intron
  ENSMUST00000133791 Lpcat1-004 73467423-73501458 retained_intron
  ENSMUST00000140431 Lpcat1-005 73502861-73513841 retained_intron
  ENSMUST00000147566 Lpcat1-002 73467231-73515112 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022099ENSMUST00000123766ENSMUST00000133791ENSMUST00000147566
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022099 9.284±5.04 15.885±1.92 6.104±0.08 21.943±2.99 18.345±7.50 10.741±2.89 1.874±0.51 4.563±0.63 18.624±21.72 207.948±56.45 0.659±0.13 14.001±6.46 8.857±1.78 0.567±0.37
ENSMUST00000123766 N/A N/A N/A 6.673±0.00 N/A N/A N/A N/A N/A N/A 0.782±0.16 4.314±0.78 10.845±5.31 N/A
ENSMUST00000133791 3.586±0.12 N/A N/A N/A 8.101±0.00 N/A 2.994±0.29 4.000±0.40 0.674±0.11 N/A N/A N/A N/A 0.621±0.00
ENSMUST00000147566 2.113±0.10 N/A N/A 8.038±0.00 5.900±2.94 2.922±0.00 1.502±0.47 1.805±0.49 0.332±0.06 N/A 0.485±0.00 5.876±0.55 4.294±1.87 0.290±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008Q6 CIL_0008Q6_0002 VISTA 13:72998274-73600313
CIL_0003AA CIL_0003AA_0002 CGP 13:73331009-73516422

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005509 IEA calcium ion binding
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005811 IEA lipid particle
GO:0008152 IEA metabolic process
GO:0008654 IDA phospholipid biosynthetic process
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016746 IEA transferase activity, transferring acyl groups
GO:0036151 IEA phosphatidylcholine acyl-chain remodeling
GO:0043129 IDA surfactant homeostasis
GO:0045732 IDA positive regulation of protein catabolic process
GO:0047159 IDA 1-alkenylglycerophosphocholine O-acyltransferase activity
GO:0047184 IDA 1-acylglycerophosphocholine O-acyltransferase activity
GO:0047191 IDA 1-alkylglycerophosphocholine O-acyltransferase activity
GO:0047192 IEA 1-alkylglycerophosphocholine O-acetyltransferase activity
GO:0060041 IMP retina development in camera-type eye
GO:2001246 IDA negative regulation of phosphatidylcholine biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011506 lpcat1 lysophosphatidylcholine acyltransferase 1 protein_coding Danio_rerio
ENSDARG00000077671 CABZ01078889.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000153395 LPCAT1 lysophosphatidylcholine acyltransferase 1 protein_coding Homo_sapiens

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