C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TRAF2 and NCK interacting kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154310 TNIK 9606 - 3:171061339-171460408 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000284483 TNIK-004 171063881-171460063 protein_coding
  ENST00000341852 TNIK-003 171063330-171460408 protein_coding
  ENST00000357327 TNIK-006 171063881-171460063 protein_coding
  ENST00000436636 TNIK-001 171061339-171460408 protein_coding
  ENST00000459881 TNIK-017 171066487-171071406 retained_intron
  ENST00000460047 TNIK-007 171063881-171460063 protein_coding
  ENST00000464785 TNIK-016 171063552-171064042 processed_transcript
  ENST00000465393 TNIK-002 171346934-171460405 protein_coding
  ENST00000468757 TNIK-012 171157551-171225711 protein_coding
  ENST00000470834 TNIK-009 171063881-171460063 protein_coding
  ENST00000475336 TNIK-005 171063881-171460063 protein_coding
  ENST00000484051 TNIK-011 171066374-171082682 retained_intron
  ENST00000487846 TNIK-015 171066470-171079583 retained_intron
  ENST00000488470 TNIK-008 171063881-171460063 protein_coding
  ENST00000496492 TNIK-010 171063261-171102072 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000284483ENST00000341852ENST00000357327ENST00000436636ENST00000468757ENST00000470834ENST00000475336ENST00000496492
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000284483 N/A N/A N/A 2.771±0.00 N/A N/A N/A N/A N/A N/A 0.935±0.00 N/A N/A N/A
ENST00000341852 N/A N/A 0.377±0.00 N/A N/A 0.795±0.00 N/A N/A N/A N/A 1.629±0.00 0.254±0.06 N/A N/A
ENST00000357327 N/A N/A 0.625±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.624±0.00 N/A
ENST00000436636 0.238±0.00 1.148±0.00 N/A 7.614±0.77 1.150±0.62 2.273±0.02 1.470±0.28 2.193±0.00 1.810±0.32 2.037±0.52 1.587±0.11 0.320±0.18 0.528±0.05 4.960±0.55
ENST00000468757 N/A N/A 2.205±0.00 N/A N/A N/A N/A N/A 2.896±0.00 N/A N/A N/A N/A N/A
ENST00000470834 0.111±0.00 N/A N/A N/A 0.860±0.00 N/A N/A N/A N/A 1.009±0.00 N/A 0.281±0.01 0.251±0.00 N/A
ENST00000475336 N/A N/A 0.704±0.00 N/A N/A N/A N/A 1.261±0.00 N/A N/A N/A N/A 0.230±0.00 3.188±0.00
ENST00000496492 N/A N/A N/A N/A 1.403±0.00 2.187±0.00 0.991±0.00 N/A 1.520±0.00 2.738±0.00 N/A N/A N/A 2.926±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008FL CIL_0008FL_0001 VISTA 3:170981727-171585717
CIL_00080K CIL_00080K_0001 VISTA 3:170993261-171598174
CIL_0007SJ CIL_0007SJ_0001 VISTA 3:171005102-171609864
CIL_00049S CIL_00049S_0002 CGP 3:171061339-171810950

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005856 IDA cytoskeleton
GO:0006468 IEA protein phosphorylation
GO:0007010 IMP cytoskeleton organization
GO:0007256 IMP activation of JNKK activity
GO:0016055 IEA Wnt signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031532 IDA actin cytoskeleton reorganization
GO:0035556 IDA intracellular signal transduction
GO:0046777 IDA protein autophosphorylation
GO:0048814 IDA regulation of dendrite morphogenesis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009031 tnikb TRAF2 and NCK interacting kinase b protein_coding Danio_rerio
ENSDARG00000056218 tnika TRAF2 and NCK interacting kinase a protein_coding Danio_rerio
ENSMUSG00000027692 Tnik TRAF2 and NCK interacting kinase protein_coding Mus_musculus

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