C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphodiesterase 1C, calmodulin-dependent 70kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154678 PDE1C 9606 - 7:31751179-32299329 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000321453 PDE1C-002 31753076-32071436 protein_coding
  ENST00000396182 PDE1C-007 31790200-32070862 protein_coding
  ENST00000396184 PDE1C-003 31783504-32071408 protein_coding
  ENST00000396189 PDE1C-004 31880849-32071433 protein_coding
  ENST00000396191 PDE1C-006 31753018-32070849 protein_coding
  ENST00000396193 PDE1C-001 31751179-32299329 protein_coding
  ENST00000464881 PDE1C-011 31873332-32078010 processed_transcript
  ENST00000478736 PDE1C-009 31847864-31850902 retained_intron
  ENST00000479980 PDE1C-010 31790171-31820919 processed_transcript
  ENST00000482681 PDE1C-008 31865017-31879284 retained_intron
  ENST00000495221 PDE1C-005 32070484-32071371 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000321453ENST00000396182ENST00000396184ENST00000396191ENST00000396193ENST00000479980
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000321453 N/A N/A 0.495±0.00 N/A N/A 0.575±0.00 N/A N/A N/A N/A N/A 0.186±0.00 N/A 0.464±0.00
ENST00000396182 N/A N/A 1.041±0.00 3.255±0.00 N/A N/A 12.455±0.00 N/A 4.810±0.00 2.010±0.00 0.019±0.00 0.790±0.00 N/A 2.352±0.82
ENST00000396184 0.110±0.00 0.425±0.00 N/A 0.831±0.00 0.241±0.00 0.353±0.00 6.711±0.00 0.005±0.00 N/A N/A N/A 0.269±0.00 0.129±0.00 0.453±0.00
ENST00000396191 N/A N/A N/A N/A 1.351±0.00 N/A N/A N/A N/A N/A N/A N/A 0.100±0.00 N/A
ENST00000396193 N/A N/A 0.412±0.00 4.699±0.00 0.356±0.04 0.459±0.00 N/A 0.431±0.00 1.269±0.00 N/A 0.126±0.00 N/A 0.056±0.00 0.672±0.40
ENST00000479980 N/A N/A N/A N/A N/A N/A N/A N/A 0.045±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000358 CIL_000358_0001 CGP 7:31686715-32299329
CIL_000359 CIL_000359_0001 CGP 7:31751179-32495283

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004114 IEA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004117 TAS calmodulin-dependent cyclic-nucleotide phosphodiesterase activity
GO:0005516 IEA calmodulin binding
GO:0005829 TAS cytosol
GO:0005929 IEA cilium
GO:0007165 TAS:IEA signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007608 IEA sensory perception of smell
GO:0008152 IEA metabolic process
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012490 PDE1C (1 of 2) phosphodiesterase 1C, calmodulin-dependent 70kDa protein_coding Danio_rerio
ENSDARG00000067683 PDE1C (2 of 2) phosphodiesterase 1C, calmodulin-dependent 70kDa protein_coding Danio_rerio
ENSMUSG00000004347 Pde1c phosphodiesterase 1C protein_coding Mus_musculus

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