C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: aminolevulinate, delta-, synthase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000335854 ALAS2-008 ENSG00000158578 9606 - X:55009089-55030977 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeColonLungPlacentaTestisENST00000335854
Transcript ID Adipose Colon Lung Placenta Testis
ENST00000335854 2.864±0.00 7.369±0.00 23.260±0.00 7.622±2.00 2.286±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YC CIL_0000YC_0001 CGP X:55000357-55031064

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0003870 IDA:IEA 5-aminolevulinate synthase activity
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005759 TAS:IEA mitochondrial matrix
GO:0006778 TAS:IEA porphyrin-containing compound metabolic process
GO:0006782 IEA protoporphyrinogen IX biosynthetic process
GO:0006783 ISS heme biosynthetic process
GO:0006879 ISS cellular iron ion homeostasis
GO:0008152 IEA metabolic process
GO:0009058 IEA biosynthetic process
GO:0016594 ISS glycine binding
GO:0030170 IEA pyridoxal phosphate binding
GO:0030218 ISS erythrocyte differentiation
GO:0032364 NAS oxygen homeostasis
GO:0033014 IEA tetrapyrrole biosynthetic process
GO:0042541 ISS hemoglobin biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0050662 ISS coenzyme binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000112715 Alas2-002 protein_coding Mus_musculus 0 1742
ENSMUST00000066337 Alas2-001 protein_coding Mus_musculus 0 1742
ENSMUST00000142474 Alas2-004 processed_transcript Mus_musculus 0 483
ENSMUST00000134670 Alas2-003 retained_intron Mus_musculus 0 252

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