C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho GTPase activating protein 27
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000159314 ARHGAP27 9606 - 17:45393902-45434421 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000290470 ARHGAP27-201 45429353-45432916 protein_coding
  ENST00000376922 ARHGAP27-001 45393909-45425631 protein_coding
  ENST00000428638 ARHGAP27-202 45393902-45430297 protein_coding
  ENST00000524404 ARHGAP27-005 45402714-45425616 nonsense_mediated_decay
  ENST00000526484 ARHGAP27-007 45397965-45404186 retained_intron
  ENST00000527678 ARHGAP27-012 45404475-45432853 retained_intron
  ENST00000528273 ARHGAP27-011 45429352-45434421 protein_coding
  ENST00000528384 ARHGAP27-006 45394943-45405934 protein_coding
  ENST00000528677 ARHGAP27-004 45404445-45410426 protein_coding
  ENST00000529357 ARHGAP27-002 45397514-45410386 retained_intron
  ENST00000531735 ARHGAP27-010 45393909-45432349 retained_intron
  ENST00000532038 ARHGAP27-003 45393902-45410424 protein_coding
  ENST00000532667 ARHGAP27-008 45402774-45404702 retained_intron
  ENST00000532891 ARHGAP27-009 45395456-45430279 protein_coding
  ENST00000579357 ARHGAP27-016 45407533-45410385 retained_intron
  ENST00000581638 ARHGAP27-014 45396063-45396770 retained_intron
  ENST00000581991 ARHGAP27-015 45395455-45396163 retained_intron
  ENST00000582826 ARHGAP27-013 45397205-45403668 processed_transcript
  ENST00000590026 ARHGAP27-017 45395427-45395908 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376922ENST00000428638ENST00000528384ENST00000528677ENST00000529357ENST00000532038ENST00000532667ENST00000532891ENST00000579357ENST00000581638
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376922 N/A 4.232±0.00 N/A 1.567±0.00 N/A 2.459±0.60 1.870±0.00 4.353±4.17 0.997±0.00 N/A N/A 4.265±2.42 4.975±1.28 1.630±0.00
ENST00000428638 N/A N/A N/A N/A 1.260±0.25 N/A 1.038±0.00 N/A 0.788±0.00 7.703±6.87 N/A 4.688±3.81 0.754±0.00 N/A
ENST00000528384 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.897±0.00 1.803±0.00
ENST00000528677 N/A N/A N/A N/A N/A N/A N/A 0.751±0.00 N/A N/A N/A N/A N/A N/A
ENST00000529357 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.768±0.00 N/A 10.459±0.00 N/A N/A
ENST00000532038 1.413±0.00 N/A N/A 0.537±0.00 1.652±0.89 N/A 0.456±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000532667 N/A N/A 1.429±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000532891 3.046±0.00 N/A N/A N/A N/A N/A N/A 0.529±0.00 N/A N/A N/A 1.652±0.00 N/A N/A
ENST00000579357 N/A N/A N/A N/A 0.724±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000581638 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.151±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002S1 CIL_0002S1_0001 CGP 17:45263121-45434421
CIL_0004D9 CIL_0004D9_0002 CGP 17:45393902-45490749

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005096 IEA GTPase activator activity
GO:0005515 IEA protein binding
GO:0005622 ISS intracellular
GO:0005737 IEA cytoplasm
GO:0006898 ISS receptor-mediated endocytosis
GO:0007165 IEA signal transduction
GO:0016020 IEA membrane
GO:0017124 ISS SH3 domain binding
GO:0030675 ISS Rac GTPase activator activity
GO:0032855 ISS positive regulation of Rac GTPase activity
GO:0043089 ISS positive regulation of Cdc42 GTPase activity
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061798 arhgap27l Rho GTPase activating protein 27, like protein_coding Danio_rerio
ENSDARG00000086142 arhgap27 Rho GTPase activating protein 27 protein_coding Danio_rerio
ENSMUSG00000034255 Arhgap27 Rho GTPase activating protein 27 protein_coding Mus_musculus

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