C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: IKAROS family zinc finger 3 (Aiolos)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000161405 IKZF3 9606 - 17:39757721-39864188 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000293068 IKZF3-008 39765284-39864188 nonsense_mediated_decay
  ENST00000346243 IKZF3-004 39765790-39864126 protein_coding
  ENST00000346872 IKZF3-001 39764945-39864188 protein_coding
  ENST00000348427 IKZF3-007 39765284-39864188 nonsense_mediated_decay
  ENST00000350532 IKZF3-005 39765790-39864126 protein_coding
  ENST00000351680 IKZF3-003 39765790-39864126 protein_coding
  ENST00000377944 IKZF3-011 39765284-39864188 protein_coding
  ENST00000377945 IKZF3-009 39765284-39864188 protein_coding
  ENST00000377952 IKZF3-014 39765284-39864188 protein_coding
  ENST00000377958 IKZF3-012 39765284-39864188 protein_coding
  ENST00000394189 IKZF3-010 39765284-39864188 protein_coding
  ENST00000439016 IKZF3-015 39765790-39864127 protein_coding
  ENST00000439167 IKZF3-002 39765284-39864188 protein_coding
  ENST00000467757 IKZF3-006 39765790-39864126 protein_coding
  ENST00000535189 IKZF3-013 39765284-39864188 protein_coding
  ENST00000583368 IKZF3-016 39765496-39778225 protein_coding
  ENST00000623724 IKZF3-201 39757721-39864188 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000293068ENST00000346872ENST00000348427ENST00000377952ENST00000583368ENST00000623724
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000293068 N/A N/A 0.028±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000346872 N/A 0.322±0.00 N/A 1.367±0.00 1.763±0.00 N/A 0.289±0.00 0.344±0.00 2.277±0.00 N/A N/A 0.552±0.00
ENST00000348427 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.882±0.00 N/A
ENST00000377952 N/A N/A N/A N/A N/A 0.224±0.00 N/A N/A N/A N/A N/A N/A
ENST00000583368 N/A N/A N/A 1.708±0.00 N/A N/A 1.657±0.00 0.935±0.00 2.145±0.00 N/A N/A N/A
ENST00000623724 0.207±0.00 0.013±0.00 0.035±0.00 0.242±0.00 0.126±0.00 N/A N/A N/A N/A 0.045±0.00 N/A 0.261±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00080Z CIL_00080Z_0001 VISTA 17:39318232-39918735
CIL_00098W CIL_00098W_0001 VISTA 17:39359510-39962707
CIL_0007WH CIL_0007WH_0001 VISTA 17:39374871-39978277
CIL_0002PT CIL_0002PT_0001 CGP 17:39737927-39864188
CIL_0002PS CIL_0002PS_0001 CGP 17:39757721-39877896

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0007498 TAS mesoderm development
GO:0030888 ISS regulation of B cell proliferation
GO:0042113 IEA B cell activation
GO:0042803 IDA protein homodimerization activity
GO:0042981 IMP regulation of apoptotic process
GO:0043565 ISS sequence-specific DNA binding
GO:0045577 ISS regulation of B cell differentiation
GO:0045619 ISS regulation of lymphocyte differentiation
GO:0046872 IEA metal ion binding
GO:0046982 IDA protein heterodimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000018168 Ikzf3 IKAROS family zinc finger 3 protein_coding Mus_musculus

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