C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rac GTPase activating protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000312377 RACGAP1-001 ENSG00000161800 9606 - 12:49989162-50025461 protein_coding

Homo sapiens EnsemblGRCh38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartLiverLungOvaryPlacentaTestisENST00000312377
Transcript ID Adipose Adrenal Brain Breast Colon Heart Liver Lung Ovary Placenta Testis
ENST00000312377 1.272±0.00 0.370±0.00 2.270±0.00 1.209±0.91 1.366±0.00 0.607±0.28 0.735±0.00 1.091±0.00 7.323±6.99 4.307±2.04 22.777±8.78

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PE CIL_0008PE_0001 VISTA 12:49905565-50507504
CIL_0008CC CIL_0008CC_0001 VISTA 12:49906068-50507455
CIL_000720 CIL_000720_0001 CGP 12:49961870-49977139
CIL_00071X CIL_00071X_0001 CGP 12:49967194-50033136
CIL_00071Y CIL_00071Y_0001 CGP 12:49976923-50083611

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000281 IDA mitotic cytokinesis
GO:0000915 IMP actomyosin contractile ring assembly
GO:0005096 IDA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005547 IDA phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0005874 IEA microtubule
GO:0007018 TAS microtubule-based movement
GO:0007108 IMP cytokinesis, initiation of separation
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007283 IEP spermatogenesis
GO:0007405 ISS neuroblast proliferation
GO:0007596 TAS blood coagulation
GO:0008017 IDA microtubule binding
GO:0008272 IDA sulfate transport
GO:0009790 ISS embryo development
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019901 IPI protein kinase binding
GO:0030496 IDA midbody
GO:0031234 IDA extrinsic component of cytoplasmic side of plasma membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0032154 IDA cleavage furrow
GO:0032467 IMP positive regulation of cytokinesis
GO:0035556 IEA intracellular signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043014 IDA alpha-tubulin binding
GO:0043015 IDA gamma-tubulin binding
GO:0043547 IEA positive regulation of GTPase activity
GO:0046872 IEA metal ion binding
GO:0048487 IDA beta-tubulin binding
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0051233 IDA spindle midzone
GO:0051256 IDA spindle midzone assembly involved in mitosis
GO:0051988 IMP regulation of attachment of spindle microtubules to kinetochore
GO:0070062 IDA extracellular vesicular exosome
GO:0072686 IMP mitotic spindle
GO:0097149 IDA centralspindlin complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000171702 Racgap1-001 protein_coding Mus_musculus 0 1844
ENSMUST00000023756 Racgap1-002 protein_coding Mus_musculus 0 1840
ENSMUST00000171017 Racgap1-007 retained_intron Mus_musculus 0 821
ENSMUST00000169810 Racgap1-011 protein_coding Mus_musculus 0 713
ENSMUST00000165745 Racgap1-014 retained_intron Mus_musculus 0 597
ENSMUST00000168065 Racgap1-004 nonsense_mediated_decay Mus_musculus 0 575
ENSMUST00000170369 Racgap1-003 retained_intron Mus_musculus 0 575
ENSMUST00000165730 Racgap1-010 nonsense_mediated_decay Mus_musculus 0 483
ENSMUST00000164983 Racgap1-009 nonsense_mediated_decay Mus_musculus 0 446

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