C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Janus kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000342505 JAK1-001 ENSG00000162434 9606 - 1:64833229-64966504 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000342505
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000342505 49.588±0.00 26.708±0.00 5.700±0.00 10.164±3.11 19.008±8.78 16.207±9.65 16.615±9.03 19.308±4.81 13.320±6.29 34.351±8.89 19.748±11.79 17.262±8.01 21.246±1.53 27.142±3.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000268 CIL_000268_0001 CGP 1:64745095-64966504
CIL_000269 CIL_000269_0001 CGP 1:64833229-65232145

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005131 ISS growth hormone receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005925 IDA focal adhesion
GO:0006468 TAS:IEA protein phosphorylation
GO:0007167 IEA enzyme linked receptor protein signaling pathway
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019903 IPI protein phosphatase binding
GO:0031730 IEA CCR5 chemokine receptor binding
GO:0035556 IEA intracellular signal transduction
GO:0038110 IDA interleukin-2-mediated signaling pathway
GO:0046677 IDA response to antibiotic
GO:0046777 IEA protein autophosphorylation
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060334 TAS regulation of interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0060338 TAS regulation of type I interferon-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102781 Jak1-001 protein_coding Mus_musculus 0 4488
ENSMUST00000136167 Jak1-003 processed_transcript Mus_musculus 0 701
ENSMUST00000147211 Jak1-002 processed_transcript Mus_musculus 0 394
ENSMUST00000149297 Jak1-006 protein_coding Mus_musculus 9e-35 154

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