C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histone deacetylase 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163517 HDAC11 9606 + 3:13479724-13506424 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295757 HDAC11-001 13480165-13506416 protein_coding
  ENST00000402259 HDAC11-004 13480282-13505071 protein_coding
  ENST00000402271 HDAC11-005 13480303-13504849 protein_coding
  ENST00000404040 HDAC11-007 13480324-13504882 protein_coding
  ENST00000404548 HDAC11-008 13480324-13504589 protein_coding
  ENST00000405025 HDAC11-009 13480376-13504543 protein_coding
  ENST00000405478 HDAC11-010 13480344-13504142 protein_coding
  ENST00000416248 HDAC11-014 13480797-13496842 protein_coding
  ENST00000418189 HDAC11-012 13480457-13496748 protein_coding
  ENST00000425430 HDAC11-006 13480306-13504956 nonsense_mediated_decay
  ENST00000433119 HDAC11-002 13479724-13505334 protein_coding
  ENST00000434848 HDAC11-013 13480700-13502939 protein_coding
  ENST00000437379 HDAC11-017 13481246-13506407 protein_coding
  ENST00000446613 HDAC11-201 13480215-13506424 protein_coding
  ENST00000455904 HDAC11-015 13481095-13502913 protein_coding
  ENST00000458642 HDAC11-011 13480333-13501699 protein_coding
  ENST00000475818 HDAC11-003 13480381-13502588 retained_intron
  ENST00000487585 HDAC11-016 13481382-13503239 retained_intron
  ENST00000495099 HDAC11-018 13496826-13502948 processed_transcript
  ENST00000498532 HDAC11-019 13496588-13504113 retained_intron
  ENST00000522202 HDAC11-020 13480411-13505233 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000295757ENST00000402259ENST00000402271ENST00000404040ENST00000405478ENST00000418189ENST00000425430ENST00000433119ENST00000437379ENST00000446613ENST00000522202
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000295757 N/A N/A N/A N/A N/A N/A 2.593±0.00 N/A N/A N/A N/A N/A N/A 4.628±0.00
ENST00000402259 N/A N/A 0.584±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 4.223±0.00 N/A N/A
ENST00000402271 N/A N/A N/A N/A N/A 0.963±0.00 0.691±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000404040 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.824±0.00 N/A
ENST00000405478 N/A N/A N/A N/A N/A N/A 0.502±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000418189 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.815±0.00 N/A N/A
ENST00000425430 N/A N/A 1.325±0.00 4.072±0.00 1.647±0.00 N/A 0.495±0.00 N/A 0.619±0.00 N/A 4.305±0.00 N/A N/A N/A
ENST00000433119 N/A N/A N/A N/A N/A N/A N/A N/A 0.353±0.00 N/A N/A 1.910±1.19 N/A 20.523±0.00
ENST00000437379 3.376±0.00 1.951±0.00 0.149±0.00 13.359±10.38 6.959±0.00 6.060±5.47 3.278±2.66 10.286±0.00 N/A 7.494±0.00 4.559±0.00 8.016±5.52 5.544±1.04 6.535±1.22
ENST00000446613 N/A N/A N/A N/A 0.997±0.00 N/A N/A N/A 1.164±0.00 N/A N/A N/A N/A N/A
ENST00000522202 N/A 1.418±0.00 N/A N/A N/A 0.290±0.00 N/A N/A N/A 0.647±0.00 1.204±0.00 2.424±0.00 N/A 13.997±6.58

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000518 CIL_000518_0001 CGP 3:13316235-13506424
CIL_0004U8 CIL_0004U8_0002 CGP 3:13479724-13638422

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 IDA histone deacetylase complex
GO:0004407 IDA histone deacetylase activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005886 IDA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008134 TAS transcription factor binding
GO:0008152 IEA metabolic process
GO:0014003 IEA oligodendrocyte development
GO:0016568 TAS chromatin modification
GO:0016575 IDA histone deacetylation
GO:0016787 IEA hydrolase activity
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0070062 IDA extracellular vesicular exosome
GO:0070932 IEA histone H3 deacetylation
GO:0070933 IEA histone H4 deacetylation
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037346 hdac11 histone deacetylase 11 protein_coding Danio_rerio
ENSDARG00000087573 HDAC11 (2 of 2) histone deacetylase 11 protein_coding Danio_rerio
ENSMUSG00000034245 Hdac11 histone deacetylase 11 protein_coding Mus_musculus

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