C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase, Mg2+/Mn2+ dependent, 1L
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163590 PPM1L 9606 + 3:160755602-161078907 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295839 PPM1L-004 160842227-161069856 protein_coding
  ENST00000464260 PPM1L-005 160842213-161071028 protein_coding
  ENST00000480117 PPM1L-003 160870598-161069844 processed_transcript
  ENST00000497343 PPM1L-002 160755602-161022462 protein_coding
  ENST00000498165 PPM1L-001 160756208-161078907 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000295839ENST00000497343ENST00000498165
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000295839 N/A N/A N/A N/A N/A N/A N/A 0.537±0.00 N/A N/A N/A N/A N/A N/A
ENST00000497343 N/A N/A 6.553±0.00 N/A 3.261±0.00 3.545±0.00 3.995±0.00 1.006±0.00 10.670±0.00 1.550±0.00 8.158±0.00 N/A N/A N/A
ENST00000498165 2.511±0.00 0.578±0.00 1.821±0.00 6.572±1.42 2.058±0.07 2.491±1.35 2.878±0.74 1.095±0.64 3.371±2.38 1.092±0.31 3.229±0.00 0.644±0.39 2.097±0.27 1.033±0.54

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004K2 CIL_0004K2_0002 CGP 3:160677159-161078907
CIL_0001Z8 CIL_0001Z8_0001 CGP 3:160755602-161105384

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0003824 IEA catalytic activity
GO:0004722 TAS protein serine/threonine phosphatase activity
GO:0005515 IEA protein binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006470 IEA protein dephosphorylation
GO:0006665 TAS sphingolipid metabolic process
GO:0007178 IEA transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0016021 IEA integral component of membrane
GO:0030148 TAS sphingolipid biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063218 ppm1la protein phosphatase, Mg2+/Mn2+ dependent, 1La protein_coding Danio_rerio
ENSDARG00000089641 ppm1lb protein phosphatase, Mg2+/Mn2+ dependent, 1Lb protein_coding Danio_rerio
ENSMUSG00000027784 Ppm1l protein phosphatase 1 (formerly 2C)-like protein_coding Mus_musculus

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