C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 1 (formerly 2C)-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027784 Ppm1l 10090 + 3:69316861-69560802 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029355 Ppm1l-001 69316861-69560802 protein_coding
  ENSMUST00000128637 Ppm1l-003 69548979-69553099 retained_intron
  ENSMUST00000134037 Ppm1l-002 69542432-69552918 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029355
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029355 3.262±1.86 2.763±0.31 3.741±0.46 7.044±1.30 2.232±0.77 1.876±0.21 3.686±0.70 2.185±0.24 1.753±0.54 2.890±0.55 12.498±1.33 4.403±0.71 0.640±0.30 0.719±0.23

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004K2 CIL_0004K2_0003 CGP 3:69222419-69560802
CIL_0001Z8 CIL_0001Z8_0002 CGP 3:69316861-69598861

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IPI MAPK cascade
GO:0004722 IDA protein serine/threonine phosphatase activity
GO:0005515 IPI protein binding
GO:0006470 IEA protein dephosphorylation
GO:0007178 IDA transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0016021 IEA integral component of membrane
GO:0046872 IEA metal ion binding
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063218 ppm1la protein phosphatase, Mg2+/Mn2+ dependent, 1La protein_coding Danio_rerio
ENSDARG00000089641 ppm1lb protein phosphatase, Mg2+/Mn2+ dependent, 1Lb protein_coding Danio_rerio
ENSG00000163590 PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L protein_coding Homo_sapiens

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