C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein phosphatase, Mg2+/Mn2+ dependent, 1L
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000498165 PPM1L-001 ENSG00000163590 9606 + 3:160756208-161078907 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000498165
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000498165 2.511±0.00 0.578±0.00 1.821±0.00 6.572±1.42 2.058±0.07 2.491±1.35 2.878±0.74 1.095±0.64 3.371±2.38 1.092±0.31 3.229±0.00 0.644±0.39 2.097±0.27 1.033±0.54

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004K2 CIL_0004K2_0002 CGP 3:160677159-161078907
CIL_0001Z8 CIL_0001Z8_0001 CGP 3:160755602-161105384

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0003824 IEA catalytic activity
GO:0004722 TAS protein serine/threonine phosphatase activity
GO:0005515 IEA protein binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006470 IEA protein dephosphorylation
GO:0006665 TAS sphingolipid metabolic process
GO:0007178 IEA transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0016021 IEA integral component of membrane
GO:0030148 TAS sphingolipid biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000029355 Ppm1l-001 protein_coding Mus_musculus 0 1611
ENSDART00000092182 ppm1la-001 protein_coding Danio_rerio 0 706
ENSMUST00000128637 Ppm1l-003 retained_intron Mus_musculus 0 582
ENSMUST00000134037 Ppm1l-002 protein_coding Mus_musculus 0 326

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