C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, kainate 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164418 GRIK2 9606 + 6:101398788-102070083 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000318991 GRIK2-201 101621948-102070083 protein_coding
  ENST00000358361 GRIK2-008 101398793-101745143 protein_coding
  ENST00000369134 GRIK2-202 101621948-102070083 protein_coding
  ENST00000369137 GRIK2-203 101621948-102070083 protein_coding
  ENST00000369138 GRIK2-003 101398788-102070083 protein_coding
  ENST00000413795 GRIK2-002 101398788-102070083 protein_coding
  ENST00000421544 GRIK2-001 101398788-102070083 protein_coding
  ENST00000436862 GRIK2-005 101818370-101890384 protein_coding
  ENST00000455610 GRIK2-004 101676769-101859370 protein_coding
  ENST00000487161 GRIK2-006 101928143-102035541 retained_intron
  ENST00000487395 GRIK2-007 101927779-101993842 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000318991ENST00000358361ENST00000369134ENST00000369137ENST00000369138ENST00000413795ENST00000421544ENST00000436862ENST00000455610ENST00000487161
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000318991 0.045±0.00 N/A N/A N/A 0.205±0.00 0.143±0.00 0.374±0.00 0.232±0.00 0.157±0.00 0.056±0.00 N/A 0.172±0.00 N/A 0.085±0.00
ENST00000358361 0.031±0.00 0.111±0.00 N/A N/A 0.087±0.03 N/A 0.205±0.00 0.309±0.00 0.060±0.00 0.444±0.31 N/A 0.098±0.00 N/A 0.202±0.00
ENST00000369134 N/A N/A 0.183±0.00 2.642±2.00 N/A N/A N/A N/A 0.020±0.00 N/A N/A N/A 0.073±0.00 N/A
ENST00000369137 N/A N/A N/A N/A N/A 0.175±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000369138 N/A N/A N/A N/A N/A N/A 0.744±0.59 N/A N/A 0.067±0.00 N/A 0.168±0.07 0.219±0.08 0.545±0.00
ENST00000413795 N/A N/A N/A N/A 0.049±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000421544 N/A N/A N/A 2.457±0.00 0.011±0.00 0.210±0.00 N/A N/A N/A N/A N/A N/A 0.372±0.08 N/A
ENST00000436862 N/A N/A N/A N/A N/A 0.801±0.00 N/A N/A N/A N/A N/A 0.026±0.00 N/A N/A
ENST00000455610 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.769±0.00 N/A N/A N/A
ENST00000487161 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.596±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008LJ CIL_0008LJ_0001 VISTA 6:100995648-101597358

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001662 IEA behavioral fear response
GO:0004970 IEA ionotropic glutamate receptor activity
GO:0005234 IEA extracellular-glutamate-gated ion channel activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006810 NAS transport
GO:0006874 IEA cellular calcium ion homeostasis
GO:0006886 IEA intracellular protein transport
GO:0007165 IEA signal transduction
GO:0007215 TAS glutamate receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0008066 IEA glutamate receptor activity
GO:0008328 IEA ionotropic glutamate receptor complex
GO:0014069 IEA postsynaptic density
GO:0015277 IDA kainate selective glutamate receptor activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019228 IEA neuronal action potential
GO:0030054 IEA cell junction
GO:0030165 IEA PDZ domain binding
GO:0030424 IEA axon
GO:0030425 IBA dendrite
GO:0031624 IEA ubiquitin conjugating enzyme binding
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032839 IEA dendrite cytoplasm
GO:0032983 IBA kainate selective glutamate receptor complex
GO:0034220 IEA ion transmembrane transport
GO:0035235 IEA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0042391 IEA regulation of membrane potential
GO:0042734 IBA presynaptic membrane
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043025 IEA neuronal cell body
GO:0043113 IEA receptor clustering
GO:0043195 IEA terminal bouton
GO:0043204 IEA perikaryon
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0045202 IEA synapse
GO:0045211 IBA postsynaptic membrane
GO:0046328 IEA regulation of JNK cascade
GO:0048169 IEA regulation of long-term neuronal synaptic plasticity
GO:0048172 IMP regulation of short-term neuronal synaptic plasticity
GO:0050804 IDA regulation of synaptic transmission
GO:0050806 IMP positive regulation of synaptic transmission
GO:0051402 IEA neuron apoptotic process
GO:0051967 IEA negative regulation of synaptic transmission, glutamatergic
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential
GO:0060080 IEA regulation of inhibitory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074515 GRIK2 (1 of 2) glutamate receptor, ionotropic, kainate 2 protein_coding Danio_rerio
ENSMUSG00000056073 Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) protein_coding Mus_musculus

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