C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, ionotropic, kainate 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000421544 GRIK2-001 ENSG00000164418 9606 + 6:101398788-102070083 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonPlacentaENST00000421544
Transcript ID Brain Breast Colon Placenta
ENST00000421544 2.457±0.00 0.011±0.00 0.210±0.00 0.372±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008LJ CIL_0008LJ_0001 VISTA 6:100995648-101597358

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001662 IEA behavioral fear response
GO:0004970 IEA ionotropic glutamate receptor activity
GO:0005234 IEA:IBA extracellular-glutamate-gated ion channel activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006810 NAS transport
GO:0006874 IEA cellular calcium ion homeostasis
GO:0006886 IEA intracellular protein transport
GO:0007165 IEA signal transduction
GO:0007215 TAS glutamate receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0008066 IEA glutamate receptor activity
GO:0008328 IEA ionotropic glutamate receptor complex
GO:0014069 IEA postsynaptic density
GO:0015277 IDA kainate selective glutamate receptor activity
GO:0016020 IEA membrane
GO:0019228 IEA neuronal action potential
GO:0030054 IEA cell junction
GO:0030165 IEA PDZ domain binding
GO:0030424 IEA axon
GO:0030425 IBA dendrite
GO:0031624 IEA ubiquitin conjugating enzyme binding
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032839 IEA dendrite cytoplasm
GO:0032983 IBA kainate selective glutamate receptor complex
GO:0034220 IEA ion transmembrane transport
GO:0035235 IEA:IBA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0042391 IEA regulation of membrane potential
GO:0042734 IBA presynaptic membrane
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043025 IEA neuronal cell body
GO:0043113 IEA receptor clustering
GO:0043195 IEA terminal bouton
GO:0043204 IEA perikaryon
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0045202 IEA synapse
GO:0045211 IBA postsynaptic membrane
GO:0046328 IEA regulation of JNK cascade
GO:0048169 IEA regulation of long-term neuronal synaptic plasticity
GO:0048172 IMP regulation of short-term neuronal synaptic plasticity
GO:0050804 IDA regulation of synaptic transmission
GO:0050806 IMP positive regulation of synaptic transmission
GO:0051402 IEA neuron apoptotic process
GO:0051967 IEA negative regulation of synaptic transmission, glutamatergic
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential
GO:0060080 IEA regulation of inhibitory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000105487 Grik2-001 protein_coding Mus_musculus 0 4750
ENSMUST00000105484 Grik2-202 protein_coding Mus_musculus 0 4433
ENSMUST00000105485 Grik2-004 protein_coding Mus_musculus 0 3757
ENSMUST00000105486 Grik2-005 protein_coding Mus_musculus 0 3615
ENSMUST00000079751 Grik2-201 protein_coding Mus_musculus 0 3613
ENSMUST00000147808 Grik2-003 retained_intron Mus_musculus 0 1825
ENSMUST00000105483 Grik2-002 protein_coding Mus_musculus 0 1550
ENSMUST00000114137 Grik1-203 protein_coding Mus_musculus 0 1216
ENSMUST00000023652 Grik1-201 protein_coding Mus_musculus 0 1216
ENSMUST00000072256 Grik1-202 protein_coding Mus_musculus 0 1216
ENSMUST00000129279 Grik2-006 retained_intron Mus_musculus 0 235

Loading