C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: peroxisomal biogenesis factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164751 PEX2 9606 - 8:76980258-77001044 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000357039 PEX2-001 76980258-77000226 protein_coding
  ENST00000518986 PEX2-006 76983640-76986527 protein_coding
  ENST00000519956 PEX2-004 76984170-77001044 protein_coding
  ENST00000520103 PEX2-003 76982934-77000947 protein_coding
  ENST00000520203 PEX2-005 76987892-77000230 processed_transcript
  ENST00000522527 PEX2-002 76982957-77000267 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000357039ENST00000518986ENST00000519956ENST00000520103ENST00000522527
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000357039 0.882±0.00 1.396±0.00 N/A 1.249±0.00 1.363±0.03 0.807±0.07 0.677±0.30 1.629±0.18 0.851±0.00 0.913±0.00 0.829±0.00 1.076±0.20 0.929±0.04 0.975±0.30
ENST00000518986 2.756±0.00 N/A 1.068±0.00 4.806±2.41 4.424±0.00 3.986±0.00 N/A 3.364±1.48 2.659±0.00 N/A 3.058±1.02 6.302±2.61 7.708±0.00 7.017±0.00
ENST00000519956 N/A N/A N/A N/A N/A N/A 3.827±0.00 N/A 6.869±0.00 7.001±0.00 N/A 10.134±2.73 8.396±0.00 9.598±0.00
ENST00000520103 3.309±0.00 6.585±0.00 N/A 6.021±0.00 3.927±0.00 2.250±0.00 N/A 4.799±0.00 N/A N/A 2.251±0.00 2.097±0.00 2.527±0.00 3.064±0.00
ENST00000522527 2.323±0.00 1.800±0.00 1.308±0.00 2.339±0.54 5.032±0.00 1.497±0.00 2.290±0.01 1.945±0.57 N/A 3.120±0.40 2.275±0.19 3.741±0.08 4.129±1.56 1.259±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008DA CIL_0008DA_0001 VISTA 8:76385772-76988410
CIL_0008IW CIL_0008IW_0001 VISTA 8:76478447-77079543
CIL_0008U7 CIL_0008U7_0001 VISTA 8:76539317-77142107
CIL_0002OE CIL_0002OE_0001 CGP 8:76681219-77001044
CIL_0007P3 CIL_0007P3_0002 UCNEbase 8:76720446-77719456
CIL_0008QU CIL_0008QU_0001 VISTA 8:76830335-77431965

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000038 IMP very long-chain fatty acid metabolic process
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001764 IEA neuron migration
GO:0005515 IPI:IEA protein binding
GO:0005777 IEA peroxisome
GO:0005778 IDA peroxisomal membrane
GO:0005779 IMP integral component of peroxisomal membrane
GO:0006635 IMP fatty acid beta-oxidation
GO:0006699 IEA bile acid biosynthetic process
GO:0007031 IMP peroxisome organization
GO:0007399 IEA nervous system development
GO:0008270 IEA zinc ion binding
GO:0016020 IDA membrane
GO:0016558 IMP protein import into peroxisome matrix
GO:0016593 IDA Cdc73/Paf1 complex
GO:0031648 IMP protein destabilization
GO:0042632 IEA cholesterol homeostasis
GO:0045540 IEA regulation of cholesterol biosynthetic process
GO:0048147 IMP negative regulation of fibroblast proliferation
GO:0050680 IMP negative regulation of epithelial cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062421 pex2 peroxisomal biogenesis factor 2 protein_coding Danio_rerio
ENSMUSG00000040374 Pex2 peroxisomal biogenesis factor 2 protein_coding Mus_musculus

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