C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor binding SET domain protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165671 NSD1 9606 + 5:177133025-177300215 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000347982 NSD1-002 177134229-177295762 protein_coding
  ENST00000354179 NSD1-201 177133079-177300210 protein_coding
  ENST00000375350 NSD1-007 177212111-177239865 nonsense_mediated_decay
  ENST00000439151 NSD1-001 177133925-177300215 protein_coding
  ENST00000503056 NSD1-009 177265727-177280583 protein_coding
  ENST00000504457 NSD1-010 177266337-177269684 protein_coding
  ENST00000505395 NSD1-011 177266380-177269671 protein_coding
  ENST00000508029 NSD1-008 177265465-177269758 protein_coding
  ENST00000508896 NSD1-004 177133600-177209672 protein_coding
  ENST00000510954 NSD1-005 177133079-177204236 protein_coding
  ENST00000511258 NSD1-003 177134173-177137404 protein_coding
  ENST00000512992 NSD1-006 177133025-177135426 retained_intron
  ENST00000513736 NSD1-013 177288526-177292127 retained_intron
  ENST00000515735 NSD1-012 177266587-177273678 protein_coding
  ENST00000602285 NSD1-014 177133798-177136345 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000347982ENST00000354179ENST00000439151
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000347982 2.841±0.00 3.455±0.00 1.018±0.00 1.360±0.21 3.387±0.69 2.505±0.00 0.968±0.32 2.297±0.25 1.255±0.00 2.319±0.00 2.899±1.33 2.576±1.39 1.582±0.18 5.600±0.89
ENST00000354179 N/A N/A 1.293±0.00 N/A N/A 1.711±0.00 1.769±0.00 N/A N/A N/A 0.424±0.00 N/A N/A N/A
ENST00000439151 0.386±0.00 N/A N/A 1.146±0.00 1.285±0.00 0.584±0.00 0.768±0.04 1.205±0.00 1.746±0.00 2.059±0.00 N/A 1.047±0.00 0.999±0.48 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000OQ CIL_0000OQ_0002 CGP 5:177086886-177300215
CIL_0008A2 CIL_0008A2_0001 VISTA 5:177089375-177692188
CIL_0002YK CIL_0002YK_0001 CGP 5:177133025-177303744

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001702 IEA gastrulation with mouth forming second
GO:0003682 ISS chromatin binding
GO:0003712 IDA transcription cofactor activity
GO:0003714 ISS transcription corepressor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005694 IEA chromosome
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IDA:IEA zinc ion binding
GO:0010452 ISS histone H3-K36 methylation
GO:0016571 ISS histone methylation
GO:0018024 IEA histone-lysine N-methyltransferase activity
GO:0030331 ISS estrogen receptor binding
GO:0034770 ISS histone H4-K20 methylation
GO:0042054 IEA histone methyltransferase activity
GO:0042799 ISS histone methyltransferase activity (H4-K20 specific)
GO:0042974 ISS retinoic acid receptor binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046965 ISS retinoid X receptor binding
GO:0046966 ISS thyroid hormone receptor binding
GO:0046975 ISS histone methyltransferase activity (H3-K36 specific)
GO:0050681 IDA androgen receptor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060016 nsd1a nuclear receptor binding SET domain protein 1a protein_coding Danio_rerio
ENSDARG00000060705 nsd1b nuclear receptor binding SET domain protein 1b protein_coding Danio_rerio
ENSMUSG00000021488 Nsd1 nuclear receptor-binding SET-domain protein 1 protein_coding Mus_musculus

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