C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NDRG family member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165795 NDRG2 9606 - 14:21016763-21070872 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000298684 NDRG2-004 21016811-21023327 protein_coding
  ENST00000298687 NDRG2-008 21016763-21025776 protein_coding
  ENST00000350792 NDRG2-003 21016763-21025823 protein_coding
  ENST00000360463 NDRG2-002 21016772-21025819 protein_coding
  ENST00000366204 NDRG2-070 21020120-21021087 retained_intron
  ENST00000397844 NDRG2-001 21016851-21025645 protein_coding
  ENST00000397847 NDRG2-007 21016773-21025848 protein_coding
  ENST00000397851 NDRG2-010 21016773-21025105 protein_coding
  ENST00000397853 NDRG2-005 21016772-21025094 protein_coding
  ENST00000397856 NDRG2-201 21017450-21025047 protein_coding
  ENST00000397858 NDRG2-202 21016764-21025776 protein_coding
  ENST00000403829 NDRG2-016 21017221-21070872 protein_coding
  ENST00000449431 NDRG2-006 21019146-21022497 protein_coding
  ENST00000553442 NDRG2-050 21020507-21025490 protein_coding
  ENST00000553503 NDRG2-011 21016772-21025039 protein_coding
  ENST00000553563 NDRG2-058 21021841-21023522 protein_coding
  ENST00000553567 NDRG2-071 21020363-21021041 retained_intron
  ENST00000553593 NDRG2-069 21017481-21021122 protein_coding
  ENST00000553741 NDRG2-053 21020264-21024078 retained_intron
  ENST00000553784 NDRG2-057 21020533-21023740 protein_coding
  ENST00000553793 NDRG2-072 21017747-21020291 retained_intron
  ENST00000553862 NDRG2-065 21021417-21022343 retained_intron
  ENST00000553867 NDRG2-052 21019121-21025047 protein_coding
  ENST00000553900 NDRG2-033 21021712-21025061 retained_intron
  ENST00000554094 NDRG2-056 21019967-21023954 protein_coding
  ENST00000554104 NDRG2-017 21016772-21022820 protein_coding
  ENST00000554143 NDRG2-009 21016773-21025105 protein_coding
  ENST00000554277 NDRG2-077 21018799-21021831 processed_transcript
  ENST00000554379 NDRG2-061 21020798-21025093 nonsense_mediated_decay
  ENST00000554398 NDRG2-051 21020804-21024096 protein_coding
  ENST00000554415 NDRG2-023 21022147-21025692 protein_coding
  ENST00000554419 NDRG2-020 21021837-21025755 protein_coding
  ENST00000554472 NDRG2-046 21020808-21024285 protein_coding
  ENST00000554483 NDRG2-035 21020809-21025061 protein_coding
  ENST00000554489 NDRG2-043 21021857-21025000 protein_coding
  ENST00000554531 NDRG2-064 21020554-21023152 protein_coding
  ENST00000554561 NDRG2-045 21021822-21024295 protein_coding
  ENST00000554833 NDRG2-040 21022109-21025026 protein_coding
  ENST00000554893 NDRG2-037 21022088-21025033 protein_coding
  ENST00000555026 NDRG2-019 21018457-21048533 protein_coding
  ENST00000555142 NDRG2-029 21020549-21025139 protein_coding
  ENST00000555158 NDRG2-012 21016772-21025026 protein_coding
  ENST00000555384 NDRG2-039 21019948-21025033 protein_coding
  ENST00000555650 NDRG2-074 21016838-21018814 retained_intron
  ENST00000555657 NDRG2-042 21020827-21025014 protein_coding
  ENST00000555695 NDRG2-054 21019639-21024060 nonsense_mediated_decay
  ENST00000555733 NDRG2-036 21019698-21025042 protein_coding
  ENST00000555767 NDRG2-025 21020552-21025529 nonsense_mediated_decay
  ENST00000555869 NDRG2-026 21019648-21025526 protein_coding
  ENST00000556008 NDRG2-034 21017992-21025061 protein_coding
  ENST00000556147 NDRG2-013 21016773-21024964 protein_coding
  ENST00000556329 NDRG2-030 21020784-21025094 protein_coding
  ENST00000556366 NDRG2-066 21018020-21022261 protein_coding
  ENST00000556420 NDRG2-038 21020529-21025033 protein_coding
  ENST00000556457 NDRG2-024 21020829-21025532 protein_coding
  ENST00000556561 NDRG2-044 21021870-21024715 protein_coding
  ENST00000556688 NDRG2-032 21020830-21025072 protein_coding
  ENST00000556716 NDRG2-018 21016772-21020669 retained_intron
  ENST00000556924 NDRG2-027 21020576-21025289 protein_coding
  ENST00000556974 NDRG2-021 21018457-21025752 protein_coding
  ENST00000557113 NDRG2-055 21021676-21024031 retained_intron
  ENST00000557149 NDRG2-048 21020549-21024285 protein_coding
  ENST00000557167 NDRG2-049 21022880-21024284 retained_intron
  ENST00000557169 NDRG2-059 21019639-21023492 protein_coding
  ENST00000557182 NDRG2-063 21019670-21025061 protein_coding
  ENST00000557198 NDRG2-062 21020465-21025061 retained_intron
  ENST00000557264 NDRG2-047 21020559-21024285 protein_coding
  ENST00000557274 NDRG2-041 21020829-21025021 protein_coding
  ENST00000557305 NDRG2-068 21020448-21021251 retained_intron
  ENST00000557318 NDRG2-060 21021755-21025068 retained_intron
  ENST00000557353 NDRG2-014 21016773-21025061 nonsense_mediated_decay
  ENST00000557416 NDRG2-073 21017995-21020109 retained_intron
  ENST00000557616 NDRG2-031 21020827-21025081 nonsense_mediated_decay
  ENST00000557633 NDRG2-076 21016772-21022443 protein_coding
  ENST00000557669 NDRG2-022 21021587-21025732 retained_intron
  ENST00000557676 NDRG2-028 21020561-21025140 protein_coding
  ENST00000557728 NDRG2-067 21020292-21022233 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000298684ENST00000298687ENST00000350792ENST00000360463ENST00000397851ENST00000397853ENST00000397856ENST00000397858ENST00000403829ENST00000554104ENST00000554143ENST00000556147ENST00000557169ENST00000557353ENST00000557633
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000298684 N/A N/A N/A N/A N/A N/A 26.147±0.00 N/A N/A 15.916±0.00 N/A N/A N/A N/A
ENST00000298687 N/A N/A N/A N/A 1.100±0.00 N/A N/A N/A N/A N/A 55.785±0.00 2.405±0.00 N/A N/A
ENST00000350792 N/A N/A N/A N/A N/A N/A N/A N/A 3.439±0.00 N/A N/A 30.613±0.00 N/A N/A
ENST00000360463 N/A N/A N/A 81.988±32.46 N/A 36.098±0.00 N/A N/A N/A N/A N/A 27.770±0.00 N/A N/A
ENST00000397851 N/A N/A N/A N/A N/A N/A 27.480±22.51 N/A 50.411±0.00 N/A 203.786±0.00 N/A 5.036±0.00 N/A
ENST00000397853 28.283±0.00 22.100±0.00 N/A 162.760±0.00 66.438±0.00 50.389±0.00 20.570±18.27 34.861±2.09 46.896±0.00 19.621±0.00 64.842±28.98 30.467±21.14 7.502±2.47 36.285±0.00
ENST00000397856 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.033±0.00 N/A N/A
ENST00000397858 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.700±1.00 N/A
ENST00000403829 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.925±1.87 N/A
ENST00000554104 N/A N/A 7.971±0.00 N/A N/A 5.898±0.00 N/A N/A N/A 3.933±0.00 N/A 3.551±0.00 4.320±0.00 N/A
ENST00000554143 22.751±0.00 9.185±0.00 N/A 129.534±0.00 48.017±0.00 N/A 2.324±0.00 25.623±0.00 N/A 11.635±0.00 N/A 82.948±17.08 6.137±0.00 23.480±0.00
ENST00000556147 N/A N/A N/A N/A N/A 2.357±0.00 N/A N/A 1.873±0.00 N/A N/A 1.405±0.00 N/A N/A
ENST00000557169 N/A N/A N/A N/A 3.583±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000557353 13.454±0.00 N/A N/A N/A N/A 40.846±0.00 N/A N/A N/A 21.472±0.00 N/A 2.562±0.00 N/A 23.003±0.00
ENST00000557633 N/A N/A N/A 356.912±0.00 7.558±0.00 N/A N/A 133.406±0.00 N/A 13.572±0.00 141.087±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004TH CIL_0004TH_0001 CGP 14:20999255-21070872
CIL_00027R CIL_00027R_0001 CGP 14:21016763-21070872

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001818 IEA negative regulation of cytokine production
GO:0003674 ND molecular_function
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005813 IDA centrosome
GO:0005815 IDA microtubule organizing center
GO:0005829 NAS cytosol
GO:0007165 IEA signal transduction
GO:0010574 IEA regulation of vascular endothelial growth factor production
GO:0016055 IEA Wnt signaling pathway
GO:0021762 IEP substantia nigra development
GO:0030154 IEA cell differentiation
GO:0042995 IEA cell projection
GO:0048662 IEA negative regulation of smooth muscle cell proliferation
GO:0070062 IDA extracellular vesicular exosome
GO:0070373 IEA negative regulation of ERK1 and ERK2 cascade
GO:0090361 IEA regulation of platelet-derived growth factor production

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011170 ndrg2 N-myc downstream regulated gene 2 protein_coding Danio_rerio
ENSMUSG00000004558 Ndrg2 N-myc downstream regulated gene 2 protein_coding Mus_musculus

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