C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 2, subfamily C, polypeptide 19
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165841 CYP2C19 9606 + 10:94762624-94853260 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371321 CYP2C19-001 94762624-94853260 protein_coding
  ENST00000480405 CYP2C19-003 94762681-94776450 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastHeartKidneyLiverOvaryTestisENST00000371321ENST00000480405
Transcript ID Bladder Brain Breast Heart Kidney Liver Ovary Testis
ENST00000371321 0.112±0.00 0.062±0.03 0.255±0.00 0.031±0.02 61.855±0.00 N/A N/A N/A
ENST00000480405 N/A N/A N/A N/A N/A 0.130±0.00 0.434±0.00 0.028±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007H6 CIL_0007H6_0002 CGP 10:94683621-94853073
CIL_0007H6 CIL_0007H6_000A CGP 10:94688154-94853260
CIL_0007H6 CIL_0007H6_0004 CGP 10:94762624-94989390

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 IDA monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006805 TAS xenobiotic metabolic process
GO:0008202 IMP steroid metabolic process
GO:0008395 IMP steroid hydroxylase activity
GO:0016098 IDA monoterpenoid metabolic process
GO:0016491 IDA oxidoreductase activity
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0017144 IDA drug metabolic process
GO:0018675 IEA (S)-limonene 6-monooxygenase activity
GO:0018676 IEA (S)-limonene 7-monooxygenase activity
GO:0019369 TAS arachidonic acid metabolic process
GO:0019373 TAS epoxygenase P450 pathway
GO:0019825 TAS oxygen binding
GO:0019899 IPI enzyme binding
GO:0020037 IDA:IEA heme binding
GO:0042738 IDA exogenous drug catabolic process
GO:0043231 TAS intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0046483 IDA heterocycle metabolic process
GO:0052741 IEA (R)-limonene 6-monooxygenase activity
GO:0055114 IDA:IEA oxidation-reduction process
GO:0097267 TAS omega-hydroxylase P450 pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007173 cyp2y3 cytochrome P450, family 2, subfamily Y, polypeptide 3 protein_coding Danio_rerio
ENSDARG00000068493 si:zfos-411a11.2 si:zfos-411a11.2 protein_coding Danio_rerio
ENSMUSG00000003053 Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 protein_coding Mus_musculus
ENSMUSG00000025003 Cyp2c39 cytochrome P450, family 2, subfamily c, polypeptide 39 protein_coding Mus_musculus
ENSMUSG00000025004 Cyp2c40 cytochrome P450, family 2, subfamily c, polypeptide 40 protein_coding Mus_musculus
ENSMUSG00000032808 Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 protein_coding Mus_musculus
ENSMUSG00000042248 Cyp2c37 cytochrome P450, family 2. subfamily c, polypeptide 37 protein_coding Mus_musculus
ENSMUSG00000054827 Cyp2c50 cytochrome P450, family 2, subfamily c, polypeptide 50 protein_coding Mus_musculus
ENSMUSG00000062624 Cyp2c67 cytochrome P450, family 2, subfamily c, polypeptide 67 protein_coding Mus_musculus
ENSMUSG00000067225 Cyp2c54 cytochrome P450, family 2, subfamily c, polypeptide 54 protein_coding Mus_musculus
ENSMUSG00000067229 Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 protein_coding Mus_musculus
ENSMUSG00000067231 Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 protein_coding Mus_musculus
ENSMUSG00000074882 Cyp2c68 cytochrome P450, family 2, subfamily c, polypeptide 68 protein_coding Mus_musculus
ENSMUSG00000092008 Cyp2c69 cytochrome P450, family 2, subfamily c, polypeptide 69 protein_coding Mus_musculus

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