C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase C and casein kinase substrate in neurons 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165912 PACSIN3 9606 - 11:47177525-47186443 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000298838 PACSIN3-002 47177525-47186407 protein_coding
  ENST00000524509 PACSIN3-004 47182406-47186413 protein_coding
  ENST00000525725 PACSIN3-005 47180476-47185419 protein_coding
  ENST00000528201 PACSIN3-008 47179422-47186436 protein_coding
  ENST00000528462 PACSIN3-003 47177989-47185881 protein_coding
  ENST00000530405 PACSIN3-006 47182406-47183321 protein_coding
  ENST00000530513 PACSIN3-007 47179254-47186443 protein_coding
  ENST00000531226 PACSIN3-009 47180457-47186409 protein_coding
  ENST00000532457 PACSIN3-001 47177557-47186440 nonsense_mediated_decay
  ENST00000533686 PACSIN3-010 47177808-47179225 protein_coding
  ENST00000539589 PACSIN3-201 47177540-47185881 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000298838ENST00000524509ENST00000525725ENST00000528201ENST00000528462ENST00000532457ENST00000533686ENST00000539589
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000298838 11.665±0.00 0.922±0.00 N/A 7.614±5.57 14.684±0.00 30.555±0.00 27.352±24.89 5.975±3.40 9.494±8.75 6.891±5.71 134.686±106.36 20.430±8.55 24.110±7.03 7.511±6.80
ENST00000524509 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.827±0.00 N/A N/A
ENST00000525725 N/A N/A N/A N/A 0.975±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000528201 N/A N/A N/A N/A 0.642±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000528462 N/A N/A 0.370±0.00 N/A 0.814±0.00 0.908±0.00 2.978±0.00 N/A N/A N/A N/A 0.318±0.00 N/A N/A
ENST00000532457 N/A 0.761±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.225±0.00 N/A 1.789±0.00
ENST00000533686 N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.781±0.00 N/A N/A N/A N/A
ENST00000539589 1.971±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.402±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005737 ISS cytoplasm
GO:0005886 IEA plasma membrane
GO:0006897 IEA endocytosis
GO:0008092 ISS cytoskeletal protein binding
GO:0008289 IDA lipid binding
GO:0019855 ISS calcium channel inhibitor activity
GO:0045806 ISS negative regulation of endocytosis
GO:0051044 IMP positive regulation of membrane protein ectodomain proteolysis
GO:0051926 ISS negative regulation of calcium ion transport
GO:0070062 IDA extracellular vesicular exosome
GO:0097320 IEA:IDA membrane tubulation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024587 pacsin3 protein kinase C and casein kinase substrate in neurons 3 protein_coding Danio_rerio
ENSMUSG00000027257 Pacsin3 protein kinase C and casein kinase substrate in neurons 3 protein_coding Mus_musculus

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