C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAB8A, member RAS oncogene family
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167461 RAB8A 9606 + 19:16111629-16134234 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300935 RAB8A-001 16111629-16134234 protein_coding
  ENST00000586682 RAB8A-002 16111897-16133010 protein_coding
  ENST00000587156 RAB8A-007 16111897-16127661 retained_intron
  ENST00000588105 RAB8A-006 16111895-16112757 processed_transcript
  ENST00000589697 RAB8A-003 16111915-16126990 retained_intron
  ENST00000590899 RAB8A-005 16111892-16122132 retained_intron
  ENST00000592971 RAB8A-004 16127951-16132319 retained_intron

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000300935ENST00000586682ENST00000587156ENST00000590899ENST00000592971
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000300935 5.694±0.00 2.023±0.00 2.180±0.90 4.024±0.59 3.730±1.45 0.972±0.14 4.733±0.91 3.660±0.67 6.539±1.77 0.633±0.00 5.896±1.23 6.360±0.42 4.926±0.45
ENST00000586682 13.164±0.00 N/A 1.067±0.00 7.279±0.00 4.159±0.00 1.890±0.00 10.615±0.00 7.465±0.00 N/A 1.615±0.95 16.176±6.57 13.426±4.48 5.537±0.00
ENST00000587156 N/A 5.288±0.00 9.579±1.42 12.750±0.00 14.476±1.47 2.970±0.93 32.557±0.00 11.795±5.55 21.164±0.00 4.606±0.00 53.869±38.75 55.827±0.00 21.223±1.42
ENST00000590899 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 40.172±0.00 31.206±0.00
ENST00000592971 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 60.272±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000IM CIL_0000IM_0001 CGP 19:16067021-16134234
CIL_0000IL CIL_0000IL_0001 CGP 19:16111629-16158575

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000139 TAS Golgi membrane
GO:0000278 TAS mitotic cell cycle
GO:0003924 IDA:IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IDA:IEA GTP binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005813 IDA centrosome
GO:0005886 IEA plasma membrane
GO:0005929 IDA cilium
GO:0006184 IDA:IEA GTP catabolic process
GO:0006886 IEA intracellular protein transport
GO:0006904 IDA vesicle docking involved in exocytosis
GO:0006913 IEA nucleocytoplasmic transport
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007409 ISS axonogenesis
GO:0014069 IEA postsynaptic density
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0016023 IEA cytoplasmic membrane-bounded vesicle
GO:0017137 ISS Rab GTPase binding
GO:0019003 IDA GDP binding
GO:0019901 IEA protein kinase binding
GO:0030140 IEA trans-Golgi network transport vesicle
GO:0030425 IEA dendrite
GO:0030659 TAS cytoplasmic vesicle membrane
GO:0031489 IPI myosin V binding
GO:0031513 IDA nonmotile primary cilium
GO:0032869 ISS cellular response to insulin stimulus
GO:0032880 IEA regulation of protein localization
GO:0036064 IEA ciliary basal body
GO:0042384 IDA cilium assembly
GO:0043025 IEA neuronal cell body
GO:0045335 IDA phagocytic vesicle
GO:0048169 IEA regulation of long-term neuronal synaptic plasticity
GO:0048210 IDA Golgi vesicle fusion to target membrane
GO:0051223 IEA regulation of protein transport
GO:0055037 IEA recycling endosome
GO:0055038 IDA recycling endosome membrane
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome
GO:0072372 IDA primary cilium
GO:0072659 ISS protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000067920 rab8a RAB8A, member RAS oncogene family protein_coding Danio_rerio
ENSMUSG00000003037 Rab8a RAB8A, member RAS oncogene family protein_coding Mus_musculus

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