C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169750 RAC3 9606 + 17:82031624-82034204 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306897 RAC3-001 82031624-82034202 protein_coding
  ENST00000580965 RAC3-002 82032061-82033790 protein_coding
  ENST00000584341 RAC3-003 82032184-82033772 protein_coding
  ENST00000585014 RAC3-004 82032878-82034204 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306897ENST00000580965ENST00000584341ENST00000585014
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306897 2.675±0.00 N/A N/A 3.232±0.00 5.071±0.00 0.702±0.00 N/A 1.729±0.00 1.202±0.00 N/A 0.184±0.00 2.441±1.45 8.590±5.82 10.294±5.53
ENST00000580965 1.795±0.00 N/A N/A 4.308±0.00 2.378±1.66 0.559±0.00 N/A 1.375±0.00 2.665±0.00 0.574±0.00 N/A 8.467±7.38 7.710±6.12 11.973±3.05
ENST00000584341 N/A N/A 4.363±0.00 8.105±0.00 N/A 0.780±0.29 0.248±0.03 2.775±0.88 N/A 1.026±0.00 N/A 4.321±0.00 N/A N/A
ENST00000585014 1.806±0.00 0.346±0.00 0.623±0.00 N/A N/A N/A N/A N/A N/A 0.529±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004VQ CIL_0004VQ_0001 CGP 17:82023302-82034204
CIL_00043Y CIL_00043Y_0002 CGP 17:82031624-82037732

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IDA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006184 IDA:IEA GTP catabolic process
GO:0007165 IEA signal transduction
GO:0007264 IEA:TAS small GTPase mediated signal transduction
GO:0012505 IDA endomembrane system
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0030031 IDA cell projection assembly
GO:0030036 IDA actin cytoskeleton organization
GO:0030426 IDA growth cone
GO:0031175 IEA neuron projection development
GO:0031941 IDA filamentous actin
GO:0033630 IDA positive regulation of cell adhesion mediated by integrin
GO:0035556 TAS intracellular signal transduction
GO:0043005 IDA neuron projection
GO:0043025 IDA neuronal cell body
GO:0048306 IPI calcium-dependent protein binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050885 IEA neuromuscular process controlling balance
GO:0050905 IEA neuromuscular process
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0070062 IDA extracellular vesicular exosome
GO:0071944 IDA cell periphery
GO:1900026 IDA positive regulation of substrate adhesion-dependent cell spreading

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020795 rac3b ras-related C3 botulinum toxin substrate 3b (rho family, small GTP binding protein Rac3) protein_coding Danio_rerio
ENSDARG00000090062 rac3a ras-related C3 botulinum toxin substrate 3a (rho family, small GTP binding protein Rac3) protein_coding Danio_rerio
ENSMUSG00000018012 Rac3 RAS-related C3 botulinum substrate 3 protein_coding Mus_musculus

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