C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAS-related C3 botulinum substrate 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018012 Rac3 10090 + 11:120721470-120723969 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018156 Rac3-001 120721470-120723969 protein_coding
  ENSMUST00000134322 Rac3-003 120722014-120723565 processed_transcript
  ENSMUST00000142229 Rac3-002 120721573-120723606 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018156ENSMUST00000134322ENSMUST00000142229
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018156 11.466±5.10 15.415±2.88 2.648±0.00 75.831±51.40 1.755±0.00 7.339±1.35 0.857±0.19 6.719±1.26 0.729±0.24 32.866±9.82 0.300±0.10 20.073±3.39 3.803±3.74 1.467±0.01
ENSMUST00000134322 5.595±0.00 N/A N/A N/A 1.102±0.69 3.408±0.00 0.391±0.19 1.274±0.19 0.400±0.11 N/A 0.207±0.00 6.123±0.00 1.654±0.95 0.610±0.00
ENSMUST00000142229 N/A N/A 3.756±0.00 129.156±79.62 2.099±0.00 N/A 0.266±0.00 N/A 0.724±0.42 N/A 0.472±0.20 8.982±2.38 3.137±0.99 0.664±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004VQ CIL_0004VQ_0002 CGP 11:120713925-120723969
CIL_00043Y CIL_00043Y_0003 CGP 11:120721470-120727281

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 ISS GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005886 IEA plasma membrane
GO:0007264 IEA small GTPase mediated signal transduction
GO:0012505 ISS endomembrane system
GO:0030031 ISS cell projection assembly
GO:0030036 ISS actin cytoskeleton organization
GO:0030426 ISO growth cone
GO:0031175 IDA neuron projection development
GO:0031941 ISO filamentous actin
GO:0033630 ISS positive regulation of cell adhesion mediated by integrin
GO:0043005 ISO neuron projection
GO:0043025 ISO neuronal cell body
GO:0048306 IEA calcium-dependent protein binding
GO:0048471 ISS perinuclear region of cytoplasm
GO:0050885 IMP neuromuscular process controlling balance
GO:0050905 IMP neuromuscular process
GO:0070062 IEA extracellular vesicular exosome
GO:0071944 ISS cell periphery
GO:1900026 ISS positive regulation of substrate adhesion-dependent cell spreading

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020795 rac3b ras-related C3 botulinum toxin substrate 3b (rho family, small GTP binding protein Rac3) protein_coding Danio_rerio
ENSDARG00000090062 rac3a ras-related C3 botulinum toxin substrate 3a (rho family, small GTP binding protein Rac3) protein_coding Danio_rerio
ENSG00000169750 RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) protein_coding Homo_sapiens

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