C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leucine rich repeat and Ig domain containing 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169783 LINGO1 9606 - 15:77613027-77820900 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355300 LINGO1-001 77613027-77632490 protein_coding
  ENST00000557798 LINGO1-003 77614944-77634353 protein_coding
  ENST00000559893 LINGO1-004 77615722-77696495 protein_coding
  ENST00000561030 LINGO1-002 77613670-77696148 protein_coding
  ENST00000561686 LINGO1-013 77615353-77787014 protein_coding
  ENST00000562933 LINGO1-010 77615854-77820332 protein_coding
  ENST00000563316 LINGO1-007 77615877-77820871 protein_coding
  ENST00000564066 LINGO1-011 77677156-77820224 processed_transcript
  ENST00000564472 LINGO1-006 77615782-77720751 protein_coding
  ENST00000566711 LINGO1-014 77615673-77819452 protein_coding
  ENST00000567605 LINGO1-012 77677107-77819528 processed_transcript
  ENST00000567726 LINGO1-005 77615513-77707507 protein_coding
  ENST00000568951 LINGO1-009 77677109-77820854 processed_transcript
  ENST00000570216 LINGO1-008 77615833-77820900 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355300ENST00000557798ENST00000561030ENST00000561686ENST00000567726
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355300 1.468±0.00 1.892±0.00 0.030±0.00 13.808±11.69 1.800±0.00 1.066±0.00 0.413±0.00 0.766±0.00 0.322±0.00 0.099±0.00 0.220±0.00 0.925±0.66 5.206±2.55 2.087±0.00
ENST00000557798 N/A N/A 0.151±0.00 N/A N/A N/A 0.428±0.00 N/A N/A N/A 0.465±0.00 N/A 3.843±0.49 1.480±0.00
ENST00000561030 N/A 0.388±0.00 N/A 4.122±0.58 N/A 0.246±0.00 N/A N/A 0.073±0.04 N/A 0.386±0.00 1.037±0.39 3.020±0.00 1.542±0.24
ENST00000561686 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.236±0.00 N/A N/A N/A N/A
ENST00000567726 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.731±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003SZ CIL_0003SZ_0001 CGP 15:77420412-77820900

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005154 IEA epidermal growth factor receptor binding
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0016021 IEA integral component of membrane
GO:0021954 IEA central nervous system neuron development
GO:0031175 IEA neuron projection development
GO:0043491 IEA protein kinase B signaling
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048715 IEA negative regulation of oligodendrocyte differentiation
GO:0050770 TAS regulation of axonogenesis
GO:0050771 TAS negative regulation of axonogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034165 lingo1a leucine rich repeat and Ig domain containing 1a protein_coding Danio_rerio
ENSDARG00000035899 lingo1b leucine rich repeat and Ig domain containing 1b protein_coding Danio_rerio
ENSMUSG00000049556 Lingo1 leucine rich repeat and Ig domain containing 1 protein_coding Mus_musculus

Loading