C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leucine rich repeat and Ig domain containing 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000049556 Lingo1 10090 - 9:56618475-56685253 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000053568 Lingo1-001 56618475-56685253 protein_coding
  ENSMUST00000114247 Lingo1-002 56619105-56647660 protein_coding
  ENSMUST00000114256 Lingo1-003 56619088-56635628 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000053568ENSMUST00000114247ENSMUST00000114256
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000053568 0.417±0.09 0.303±0.12 0.166±0.00 9.114±1.99 0.081±0.00 0.122±0.02 0.192±0.03 0.095±0.04 0.055±0.03 N/A 0.037±0.00 0.090±0.01 0.160±0.11 0.482±0.28
ENSMUST00000114247 0.424±0.19 N/A 0.507±0.00 16.374±11.66 0.805±0.41 0.234±0.11 0.753±0.52 0.153±0.04 0.141±0.13 0.853±0.31 0.195±0.03 0.416±0.21 0.635±0.78 0.297±0.20
ENSMUST00000114256 0.390±0.00 0.523±0.31 0.556±0.05 21.551±11.01 0.143±0.00 0.456±0.00 0.258±0.00 0.082±0.03 0.187±0.10 0.509±0.05 0.169±0.04 0.267±0.10 0.285±0.20 0.245±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003SZ CIL_0003SZ_0002 CGP 9:56418644-56685253

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005154 IPI epidermal growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005886 IEA plasma membrane
GO:0016021 IEA integral component of membrane
GO:0021954 IDA central nervous system neuron development
GO:0031175 IDA neuron projection development
GO:0043491 IDA protein kinase B signaling
GO:0048715 IMP negative regulation of oligodendrocyte differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034165 lingo1a leucine rich repeat and Ig domain containing 1a protein_coding Danio_rerio
ENSDARG00000035899 lingo1b leucine rich repeat and Ig domain containing 1b protein_coding Danio_rerio
ENSG00000169783 LINGO1 leucine rich repeat and Ig domain containing 1 protein_coding Homo_sapiens

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