C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuronal PAS domain protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170485 NPAS2 9606 + 2:100820152-100996829 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335681 NPAS2-001 100820152-100996829 protein_coding
  ENST00000427413 NPAS2-004 100821025-100948299 protein_coding
  ENST00000433408 NPAS2-012 100982254-100996055 protein_coding
  ENST00000448812 NPAS2-007 100925146-100971049 protein_coding
  ENST00000450763 NPAS2-010 100974866-100993527 protein_coding
  ENST00000451740 NPAS2-005 100925162-100937842 protein_coding
  ENST00000471974 NPAS2-009 100974803-100982636 processed_transcript
  ENST00000474550 NPAS2-002 100970601-100996055 retained_intron
  ENST00000486017 NPAS2-008 100925146-100964176 processed_transcript
  ENST00000490052 NPAS2-011 100994443-100996055 processed_transcript
  ENST00000492373 NPAS2-006 100934111-100964918 processed_transcript
  ENST00000495559 NPAS2-003 100988310-100996822 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartKidneyLiverENST00000335681
Transcript ID Heart Kidney Liver
ENST00000335681 7.886±0.00 9.618±0.00 6.721±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004HH CIL_0004HH_0001 CGP 2:100562690-100996829
CIL_0008TG CIL_0008TG_0001 VISTA 2:100809636-101413030
CIL_0004HI CIL_0004HI_0001 CGP 2:100820152-101024032

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001047 ISS core promoter binding
GO:0003677 IDA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005667 IPI transcription factor complex
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007165 IEA signal transduction
GO:0007417 TAS central nervous system development
GO:0032922 ISS circadian regulation of gene expression
GO:0042745 IEA circadian sleep/wake cycle
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045475 IEA locomotor rhythm
GO:0045739 IMP positive regulation of DNA repair
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0046983 IEA protein dimerization activity
GO:0051775 IDA response to redox state
GO:0051879 IDA Hsp90 protein binding
GO:0060548 IMP negative regulation of cell death
GO:2001020 IMP regulation of response to DNA damage stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016536 npas2 neuronal PAS domain protein 2 protein_coding Danio_rerio
ENSMUSG00000026077 Npas2 neuronal PAS domain protein 2 protein_coding Mus_musculus

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