C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: suppressor of cytokine signaling 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170677 SOCS6 9606 + 18:70288901-70330200 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000397942 SOCS6-001 70288901-70330200 protein_coding
  ENST00000578377 SOCS6-003 70296599-70325351 protein_coding
  ENST00000582322 SOCS6-002 70314190-70327116 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000397942ENST00000578377ENST00000582322
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000397942 1.328±0.00 1.087±0.00 N/A 1.608±0.60 1.919±1.09 2.122±1.04 1.732±0.40 3.124±0.00 1.958±0.38 0.726±0.25 4.608±0.00 2.126±1.10 1.240±0.01 1.977±0.00
ENST00000578377 N/A N/A 3.130±0.00 N/A N/A N/A N/A 7.517±0.00 N/A N/A 2.249±0.00 N/A N/A N/A
ENST00000582322 1.155±0.00 0.648±0.00 N/A 2.481±0.30 1.327±0.00 4.656±0.00 1.400±0.36 1.504±0.00 3.078±0.00 3.617±0.00 0.801±0.00 1.958±1.01 1.564±0.38 1.247±0.23

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000019 CIL_000019_0002 CGP 18:70003793-70330200
CIL_00001A CIL_00001A_0003 CGP 18:70288901-72638521

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001772 IDA immunological synapse
GO:0005515 IPI protein binding
GO:0005737 TAS cytoplasm
GO:0006952 TAS defense response
GO:0007259 TAS JAK-STAT cascade
GO:0009968 IEA negative regulation of signal transduction
GO:0010498 IMP proteasomal protein catabolic process
GO:0016567 IEA protein ubiquitination
GO:0035556 IEA intracellular signal transduction
GO:0040008 IEA regulation of growth
GO:0050868 IEA negative regulation of T cell activation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015863 socs6b suppressor of cytokine signaling 6b protein_coding Danio_rerio
ENSDARG00000058565 BX640518.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000056153 Socs6 suppressor of cytokine signaling 6 protein_coding Mus_musculus

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