C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: suppressor of cytokine signaling 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000397942 SOCS6-001 ENSG00000170677 9606 + 18:70288901-70330200 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000397942
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000397942 1.328±0.00 1.087±0.00 1.608±0.60 1.919±1.09 2.122±1.04 1.732±0.40 3.124±0.00 1.958±0.38 0.726±0.25 4.608±0.00 2.126±1.10 1.240±0.01 1.977±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000019 CIL_000019_0002 CGP 18:70003793-70330200
CIL_00001A CIL_00001A_0003 CGP 18:70288901-72638521

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001772 IDA immunological synapse
GO:0005515 IPI protein binding
GO:0005737 TAS cytoplasm
GO:0006952 TAS defense response
GO:0007259 TAS JAK-STAT cascade
GO:0009968 IEA negative regulation of signal transduction
GO:0010498 IMP proteasomal protein catabolic process
GO:0016567 IEA protein ubiquitination
GO:0035556 IEA intracellular signal transduction
GO:0040008 IEA regulation of growth
GO:0050868 IEA negative regulation of T cell activation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000070116 Socs6-001 protein_coding Mus_musculus 0 1940
ENSMUST00000123826 Socs6-002 protein_coding Mus_musculus 0 1938
ENSMUST00000125362 Socs6-003 protein_coding Mus_musculus 0 1855
ENSDART00000081449 BX640518.1-201 protein_coding Danio_rerio 0 396

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