C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: suppressor of cytokine signaling 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000056153 Socs6 10090 - 18:88665224-88927481 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000070116 Socs6-001 88865169-88894322 protein_coding
  ENSMUST00000123826 Socs6-002 88868174-88894216 protein_coding
  ENSMUST00000125362 Socs6-003 88868495-88894352 protein_coding
  ENSMUST00000136173 Socs6-005 88668695-88894339 processed_transcript
  ENSMUST00000145120 Socs6-008 88870250-88887247 protein_coding
  ENSMUST00000147313 Socs6-007 88870765-88927481 protein_coding
  ENSMUST00000155169 Socs6-006 88665224-88758491 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000070116ENSMUST00000123826ENSMUST00000125362ENSMUST00000145120ENSMUST00000147313
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000070116 1.487±0.24 1.718±0.00 2.420±0.39 2.488±0.38 1.359±0.46 1.783±0.01 0.692±0.16 0.851±0.08 0.763±0.31 1.102±0.23 2.416±0.40 1.446±0.49 1.747±1.05 0.347±0.02
ENSMUST00000123826 4.406±1.50 5.976±2.19 N/A 0.964±0.10 8.598±4.16 12.540±2.01 0.707±0.00 1.589±0.57 1.215±0.63 4.235±0.97 N/A 11.060±4.36 2.407±0.90 0.245±0.03
ENSMUST00000125362 2.859±0.91 5.688±1.98 2.057±0.19 1.473±0.37 3.562±1.63 2.927±0.94 2.792±0.25 4.526±0.76 2.010±0.55 3.530±1.03 3.245±0.45 3.153±1.57 3.724±1.63 1.709±0.13
ENSMUST00000145120 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.799±0.00
ENSMUST00000147313 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.814±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001772 IEA immunological synapse
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0009968 IEA negative regulation of signal transduction
GO:0010498 IEA proteasomal protein catabolic process
GO:0016567 IEA protein ubiquitination
GO:0035556 IEA intracellular signal transduction
GO:0040008 IMP regulation of growth
GO:0050868 IDA negative regulation of T cell activation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015863 socs6b suppressor of cytokine signaling 6b protein_coding Danio_rerio
ENSDARG00000058565 BX640518.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000170677 SOCS6 suppressor of cytokine signaling 6 protein_coding Homo_sapiens

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