C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: HOP homeobox
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171476 HOPX 9606 - 4:56647988-56681899 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000317745 HOPX-006 56647998-56656516 protein_coding
  ENST00000337881 HOPX-003 56647988-56681899 protein_coding
  ENST00000381255 HOPX-017 56647998-56656507 protein_coding
  ENST00000381260 HOPX-008 56647998-56681707 protein_coding
  ENST00000420433 HOPX-014 56647988-56681706 protein_coding
  ENST00000503639 HOPX-001 56647998-56656304 protein_coding
  ENST00000503864 HOPX-004 56648000-56651202 retained_intron
  ENST00000506661 HOPX-018 56678758-56681297 retained_intron
  ENST00000508121 HOPX-007 56648275-56681877 protein_coding
  ENST00000553379 HOPX-010 56647998-56656487 protein_coding
  ENST00000554144 HOPX-201 56647989-56681706 protein_coding
  ENST00000555760 HOPX-016 56647998-56656522 protein_coding
  ENST00000556376 HOPX-009 56647998-56681294 protein_coding
  ENST00000556614 HOPX-015 56647998-56656525 protein_coding
  ENST00000605395 HOPX-011 56659152-56681297 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000317745ENST00000337881ENST00000381255ENST00000420433ENST00000503639ENST00000503864ENST00000506661ENST00000553379ENST00000555760ENST00000605395
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000317745 N/A 3.055±0.00 N/A 8.328±0.00 2.241±0.00 2.623±1.33 N/A 3.083±0.00 N/A N/A N/A 4.401±1.65 N/A 6.949±0.60
ENST00000337881 N/A N/A 0.195±0.00 14.772±0.00 N/A N/A 0.146±0.00 0.093±0.00 N/A 16.775±0.00 N/A 0.448±0.00 N/A N/A
ENST00000381255 1.145±0.00 2.878±0.00 N/A N/A 0.412±0.00 N/A N/A N/A 1.311±0.00 N/A N/A 3.737±0.00 8.487±0.00 N/A
ENST00000420433 N/A N/A N/A 8.970±0.00 N/A N/A 0.102±0.00 N/A N/A N/A N/A 1.468±0.00 N/A N/A
ENST00000503639 0.269±0.00 3.405±0.00 N/A 6.889±0.00 0.450±0.00 0.381±0.00 N/A 0.729±0.00 N/A N/A N/A N/A N/A N/A
ENST00000503864 N/A N/A 0.168±0.00 N/A N/A N/A N/A 0.127±0.00 N/A N/A N/A N/A N/A N/A
ENST00000506661 0.135±0.00 N/A N/A N/A 0.126±0.00 N/A 0.152±0.00 N/A 0.095±0.00 5.817±0.00 0.075±0.00 0.272±0.00 1.699±0.00 N/A
ENST00000553379 N/A N/A N/A 39.105±0.00 0.295±0.00 4.800±0.00 3.301±3.08 0.982±0.40 0.285±0.00 162.450±0.00 0.466±0.02 6.192±3.17 48.636±39.36 16.015±4.37
ENST00000555760 N/A 1.955±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.798±0.00 N/A N/A
ENST00000605395 N/A N/A 0.254±0.00 N/A N/A N/A N/A N/A N/A N/A 0.406±0.14 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008G9 CIL_0008G9_0001 VISTA 4:56396035-56999166
CIL_0001WR CIL_0001WR_0001 CGP 4:56530609-56681899

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001829 IDA trophectodermal cell differentiation
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007507 IEA heart development
GO:0008016 IEA regulation of heart contraction
GO:0016575 IEA histone deacetylation
GO:0043393 IEA regulation of protein binding
GO:0043415 IEA positive regulation of skeletal muscle tissue regeneration
GO:0045596 IDA negative regulation of cell differentiation
GO:0048286 IEA lung alveolus development
GO:0051155 IEA positive regulation of striated muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089368 hopx HOP homeobox protein_coding Danio_rerio
ENSMUSG00000059325 Hopx HOP homeobox protein_coding Mus_musculus

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