C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: talin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171914 TLN2 9606 + 15:62390526-62844631 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306829 TLN2-201 62647311-62844631 protein_coding
  ENST00000467297 TLN2-006 62763226-62766359 retained_intron
  ENST00000472902 TLN2-003 62758590-62784838 protein_coding
  ENST00000474847 TLN2-005 62649999-62658174 retained_intron
  ENST00000489129 TLN2-002 62740445-62841486 retained_intron
  ENST00000494733 TLN2-004 62727090-62841349 protein_coding
  ENST00000559174 TLN2-010 62835645-62840590 retained_intron
  ENST00000559908 TLN2-009 62733902-62739545 processed_transcript
  ENST00000561197 TLN2-008 62453592-62618430 processed_transcript
  ENST00000561311 TLN2-001 62561365-62844631 protein_coding
  ENST00000561322 TLN2-011 62390526-62476414 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306829ENST00000472902ENST00000489129ENST00000494733ENST00000559174ENST00000561311ENST00000561322
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306829 3.202±0.00 0.283±0.00 N/A 4.911±0.83 4.556±0.00 1.627±0.68 3.211±0.00 0.387±0.00 N/A 0.425±0.00 1.544±0.61 0.570±0.10 0.267±0.00 1.464±0.06
ENST00000472902 N/A N/A 8.793±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000489129 N/A N/A 1.812±0.00 N/A N/A 2.291±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000494733 6.958±0.00 0.499±0.00 2.543±0.00 5.765±2.64 7.074±5.21 2.984±0.00 4.572±0.00 13.914±0.00 1.346±0.00 0.925±0.00 1.978±0.29 1.503±0.23 1.069±0.29 3.930±0.06
ENST00000559174 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.033±0.00 4.013±0.00 N/A
ENST00000561311 1.516±0.00 0.324±0.00 N/A N/A 2.717±1.42 N/A 1.482±0.18 N/A 1.181±0.00 0.439±0.00 N/A 0.647±0.22 0.257±0.03 N/A
ENST00000561322 2.248±0.00 0.196±0.00 N/A 1.511±0.00 0.411±0.04 1.006±0.00 0.198±0.00 N/A N/A N/A N/A 0.453±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000502 CIL_000502_0002 CGP 15:62390526-63071915

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 IEA ruffle
GO:0003779 NAS:IEA actin binding
GO:0005158 IEA insulin receptor binding
GO:0005198 NAS structural molecule activity
GO:0005200 IEA structural constituent of cytoskeleton
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005886 IEA plasma membrane
GO:0005911 IC cell-cell junction
GO:0005916 IEA fascia adherens
GO:0005925 IDA:IEA focal adhesion
GO:0007016 IEA cytoskeletal anchoring at plasma membrane
GO:0007043 TAS cell-cell junction assembly
GO:0007155 NAS:IEA cell adhesion
GO:0015629 NAS actin cytoskeleton
GO:0045202 NAS synapse
GO:0051015 IEA actin filament binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017901 tln2a talin 2a protein_coding Danio_rerio
ENSDARG00000044271 TLN2 (2 of 2) talin 2 protein_coding Danio_rerio
ENSMUSG00000052698 Tln2 talin 2 protein_coding Mus_musculus

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